Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2479945..2480129 Replicon chromosome
Accession NZ_CP021907
Organism Staphylococcus aureus strain Seattle 1945 isolate G478

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CD795_RS12800 Protein ID WP_000482647.1
Coordinates 2480022..2480129 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2479945..2480005 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CD795_RS12775 2475455..2475622 - 168 Protein_2375 hypothetical protein -
CD795_RS12785 2475853..2477586 - 1734 WP_000486507.1 ABC transporter ATP-binding protein/permease -
CD795_RS12790 2477611..2479374 - 1764 WP_001064828.1 ABC transporter ATP-binding protein/permease -
- 2479945..2480005 + 61 - - Antitoxin
CD795_RS12800 2480022..2480129 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CD795_RS12805 2480263..2480649 - 387 WP_000779351.1 flippase GtxA -
CD795_RS12810 2480917..2482059 + 1143 WP_001176855.1 glycerate kinase -
CD795_RS12815 2482119..2482778 + 660 WP_000831298.1 membrane protein -
CD795_RS12820 2482960..2484171 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
CD795_RS12825 2484294..2484767 - 474 WP_000456499.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T77858 WP_000482647.1 NZ_CP021907:c2480129-2480022 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T77858 NZ_CP021907:c2480129-2480022 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT77858 NZ_CP021907:2479945-2480005 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References