Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2194785..2195047 Replicon chromosome
Accession NZ_CP021907
Organism Staphylococcus aureus strain Seattle 1945 isolate G478

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag CD795_RS11235 Protein ID WP_073392962.1
Coordinates 2194943..2195047 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2194785..2194948 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CD795_RS11215 2191025..2191690 - 666 WP_001024099.1 SDR family oxidoreductase -
CD795_RS11220 2191842..2192162 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CD795_RS11225 2192164..2193144 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
CD795_RS11230 2193410..2194501 + 1092 WP_000495684.1 hypothetical protein -
- 2194785..2194948 + 164 - - Antitoxin
CD795_RS11235 2194943..2195047 - 105 WP_073392962.1 hypothetical protein Toxin
CD795_RS11245 2195727..2195885 + 159 WP_001792784.1 hypothetical protein -
CD795_RS11255 2196544..2197401 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
CD795_RS11260 2197469..2198251 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T77855 WP_073392962.1 NZ_CP021907:c2195047-2194943 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T77855 NZ_CP021907:c2195047-2194943 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT77855 NZ_CP021907:2194785-2194948 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References