Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2181496..2181693 Replicon chromosome
Accession NZ_CP021905
Organism Staphylococcus aureus strain Seattle 1945 isolate G477

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag CD017_RS11165 Protein ID WP_073392962.1
Coordinates 2181589..2181693 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2181496..2181534 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CD017_RS11145 2177671..2178336 - 666 WP_001024099.1 SDR family oxidoreductase -
CD017_RS11150 2178488..2178808 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CD017_RS11155 2178810..2179790 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
CD017_RS11160 2180056..2181147 + 1092 WP_000495684.1 hypothetical protein -
- 2181496..2181534 + 39 - - Antitoxin
CD017_RS11165 2181589..2181693 - 105 WP_073392962.1 hypothetical protein Toxin
CD017_RS11175 2182373..2182531 + 159 WP_001792784.1 hypothetical protein -
CD017_RS11185 2183190..2184047 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
CD017_RS11190 2184115..2184897 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T77841 WP_073392962.1 NZ_CP021905:c2181693-2181589 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T77841 NZ_CP021905:c2181693-2181589 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT77841 NZ_CP021905:2181496-2181534 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References