Detailed information of TA system TA077834

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1880856..1881036
• Replicon: chromosome
• Accession: NZ_CP021905
• Organism: Staphylococcus aureus strain Seattle 1945 isolate G477

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CD017_RS14435
• Protein ID: WP_001801861.1
• Coordinates: 1880856..1880951 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1880979..1881036 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CD017_RS09355	1876000..1876626	+	627	WP_000669038.1	hypothetical protein	-
CD017_RS09360	1876667..1877011	+	345	WP_000627550.1	DUF3969 family protein	-
CD017_RS09365	1877109..1877681	+	573	Protein_1773	hypothetical protein	-
CD017_RS09370	1877830..1879197	-	1368	WP_001093574.1	FRG domain-containing protein	-
CD017_RS09375	1879197..1879766	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
CD017_RS09380	1879959..1880405	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
CD017_RS14435	1880856..1880951	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1880979..1881036	-	58	-	-	Antitoxin
CD017_RS09390	1881074..1881175	+	102	WP_001791232.1	hypothetical protein	-
CD017_RS09395	1881350..1881793	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
CD017_RS09400	1881793..1882236	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
CD017_RS09405	1882236..1882678	-	443	Protein_1781	DUF1433 domain-containing protein	-
CD017_RS09410	1883203..1885612	+	2410	Protein_1782	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T77834 WP_001801861.1 NZ_CP021905:1880856-1880951 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T77834 NZ_CP021905:1880856-1880951 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT77834 NZ_CP021905:c1881036-1880979 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin