Detailed information of TA system
Overview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 1374932..1375550 | Replicon | chromosome |
Accession | NZ_CP021800 | ||
Organism | Sinorhizobium meliloti strain USDA1021 |
Toxin (Protein)
Gene name | higB | Uniprot ID | Q92R61 |
Locus tag | CDO29_RS07000 | Protein ID | WP_010969011.1 |
Coordinates | 1374932..1375228 (+) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | CDO29_RS07005 | Protein ID | WP_010969010.1 |
Coordinates | 1375242..1375550 (+) | Length | 103 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CDO29_RS06975 | 1370245..1370733 | + | 489 | WP_013844230.1 | BA14K family protein | - |
CDO29_RS06980 | 1370947..1371996 | + | 1050 | WP_013844229.1 | porin | - |
CDO29_RS06985 | 1372037..1373104 | + | 1068 | WP_017265823.1 | site-specific integrase | - |
CDO29_RS06990 | 1373214..1374251 | - | 1038 | WP_003527304.1 | porin | - |
CDO29_RS06995 | 1374579..1374884 | + | 306 | WP_088203194.1 | hypothetical protein | - |
CDO29_RS07000 | 1374932..1375228 | + | 297 | WP_010969011.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CDO29_RS07005 | 1375242..1375550 | + | 309 | WP_010969010.1 | HigA family addiction module antidote protein | Antitoxin |
CDO29_RS07010 | 1375540..1375791 | + | 252 | WP_042708639.1 | hypothetical protein | - |
CDO29_RS07020 | 1376130..1377104 | - | 975 | WP_164832917.1 | non-homologous end-joining DNA ligase | - |
CDO29_RS36925 | 1377208..1377378 | + | 171 | WP_088203196.1 | hypothetical protein | - |
CDO29_RS07030 | 1377371..1377739 | + | 369 | WP_088203197.1 | hypothetical protein | - |
CDO29_RS07035 | 1378274..1378639 | - | 366 | WP_014526862.1 | hypothetical protein | - |
CDO29_RS07040 | 1378698..1378940 | - | 243 | WP_088203198.1 | hypothetical protein | - |
CDO29_RS07050 | 1379061..1380029 | - | 969 | WP_088203199.1 | chitinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11677.11 Da Isoelectric Point: 6.7260
>T77448 WP_010969011.1 NZ_CP021800:1374932-1375228 [Sinorhizobium meliloti]
VIVGFRDDWLRTFFVDDVRSRNIPYDLEARLFRKLQMIDDAATDQDLRVPPSNHFEKLRGNLAGLHSIRVNQQWRLIFRW
DGTRGEADGIYLDDHSYR
VIVGFRDDWLRTFFVDDVRSRNIPYDLEARLFRKLQMIDDAATDQDLRVPPSNHFEKLRGNLAGLHSIRVNQQWRLIFRW
DGTRGEADGIYLDDHSYR
Download Length: 297 bp
>T77448 NZ_CP021800:1374932-1375228 [Sinorhizobium meliloti]
GTGATCGTAGGCTTTCGGGACGACTGGCTTCGGACCTTCTTTGTGGATGATGTCCGTTCCCGTAACATCCCGTACGATCT
TGAAGCTCGGTTGTTCCGCAAGCTCCAGATGATTGACGATGCCGCAACCGACCAAGACTTGCGCGTGCCGCCCAGCAATC
ACTTCGAGAAGCTGCGCGGCAATCTGGCGGGGCTGCATTCGATCCGCGTCAACCAGCAATGGCGGCTGATCTTCCGCTGG
GATGGGACGCGCGGAGAGGCCGACGGGATTTATCTGGACGATCACAGCTACCGATGA
GTGATCGTAGGCTTTCGGGACGACTGGCTTCGGACCTTCTTTGTGGATGATGTCCGTTCCCGTAACATCCCGTACGATCT
TGAAGCTCGGTTGTTCCGCAAGCTCCAGATGATTGACGATGCCGCAACCGACCAAGACTTGCGCGTGCCGCCCAGCAATC
ACTTCGAGAAGCTGCGCGGCAATCTGGCGGGGCTGCATTCGATCCGCGTCAACCAGCAATGGCGGCTGATCTTCCGCTGG
GATGGGACGCGCGGAGAGGCCGACGGGATTTATCTGGACGATCACAGCTACCGATGA
Antitoxin
Download Length: 103 a.a. Molecular weight: 11588.44 Da Isoelectric Point: 11.0603
>AT77448 WP_010969010.1 NZ_CP021800:1375242-1375550 [Sinorhizobium meliloti]
MLTTKRKPATVGEILTEEFMRPMGLTQGALAEAMGVQRKHVNELCGNRRNVTAATALILARVFGNSPDFWLNVQRRNDLW
LVMNTPKERERIERARPLENAA
MLTTKRKPATVGEILTEEFMRPMGLTQGALAEAMGVQRKHVNELCGNRRNVTAATALILARVFGNSPDFWLNVQRRNDLW
LVMNTPKERERIERARPLENAA
Download Length: 309 bp
>AT77448 NZ_CP021800:1375242-1375550 [Sinorhizobium meliloti]
ATGCTGACCACCAAGCGCAAGCCGGCGACTGTCGGCGAGATACTGACTGAAGAGTTCATGCGGCCGATGGGATTGACGCA
GGGCGCGCTCGCCGAGGCGATGGGCGTCCAGCGCAAGCACGTCAACGAATTATGCGGCAACCGCAGGAACGTGACGGCGG
CGACGGCGCTGATCCTCGCCCGCGTGTTCGGCAACAGCCCGGACTTCTGGCTCAATGTGCAGAGGCGCAACGATCTTTGG
CTGGTGATGAATACGCCAAAGGAACGTGAGCGGATCGAGCGCGCGCGTCCGTTGGAGAATGCAGCCTGA
ATGCTGACCACCAAGCGCAAGCCGGCGACTGTCGGCGAGATACTGACTGAAGAGTTCATGCGGCCGATGGGATTGACGCA
GGGCGCGCTCGCCGAGGCGATGGGCGTCCAGCGCAAGCACGTCAACGAATTATGCGGCAACCGCAGGAACGTGACGGCGG
CGACGGCGCTGATCCTCGCCCGCGTGTTCGGCAACAGCCCGGACTTCTGGCTCAATGTGCAGAGGCGCAACGATCTTTGG
CTGGTGATGAATACGCCAAAGGAACGTGAGCGGATCGAGCGCGCGCGTCCGTTGGAGAATGCAGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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