Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1516199..1516901 Replicon chromosome
Accession NZ_CP021648
Organism Acidovorax sp. T1

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag CCX87_RS07220 Protein ID WP_087745047.1
Coordinates 1516199..1516501 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag CCX87_RS07225 Protein ID WP_087745049.1
Coordinates 1516503..1516901 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCX87_RS07210 1512165..1514624 + 2460 WP_087745043.1 DEAD/DEAH box helicase family protein -
CCX87_RS07215 1514714..1516174 + 1461 WP_087745045.1 type I restriction-modification system subunit M -
CCX87_RS07220 1516199..1516501 + 303 WP_087745047.1 type II toxin-antitoxin system MqsR family toxin Toxin
CCX87_RS07225 1516503..1516901 + 399 WP_087745049.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
CCX87_RS07230 1517064..1517543 + 480 WP_087745051.1 hypothetical protein -
CCX87_RS07235 1517489..1518253 - 765 WP_056269326.1 IS21-like element helper ATPase IstB -
CCX87_RS07240 1518333..1519883 - 1551 Protein_1424 IS21 family transposase -
CCX87_RS07245 1519916..1521391 + 1476 WP_087745053.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1517489..1517986 497


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(3-99)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10875.68 Da        Isoelectric Point: 8.2817

>T76885 WP_087745047.1 NZ_CP021648:1516199-1516501 [Acidovorax sp. T1]
MGKSTPHCKLTVVQGLVQAGAVRATGSAFVGARELGINDLAGMCAVVMSLTSADFYKSMTTHADHRIWQDVYRARTAWGQ
AVYLKLTVIDDVLIVCFKEL

Download         Length: 303 bp

>T76885 NZ_CP021648:1516199-1516501 [Acidovorax sp. T1]
ATGGGAAAGAGCACACCGCATTGCAAGCTAACCGTCGTTCAGGGTTTGGTTCAGGCCGGTGCCGTGCGTGCCACGGGTAG
CGCATTTGTCGGTGCGCGTGAACTGGGCATCAACGACCTTGCGGGCATGTGCGCCGTGGTCATGTCGCTGACCAGTGCCG
ACTTTTACAAAAGCATGACGACCCATGCAGACCACCGAATCTGGCAAGACGTGTACCGCGCACGCACGGCCTGGGGCCAG
GCGGTGTATCTGAAACTGACCGTCATTGACGATGTATTGATTGTTTGCTTCAAGGAGCTCTGA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14547.62 Da        Isoelectric Point: 5.7775

>AT76885 WP_087745049.1 NZ_CP021648:1516503-1516901 [Acidovorax sp. T1]
MKCPVCGAAELIHDTRDETYTYKGETTVIPAVTGDYCPACSEVLLDREQGDRYSELVGAFQRQVNAAFVAPGYITEVRKK
LALDQREAAEIFGGGVNAFSRYETGKTKPPLALVKLLKVLDRHPELLAEVRS

Download         Length: 399 bp

>AT76885 NZ_CP021648:1516503-1516901 [Acidovorax sp. T1]
ATGAAATGTCCCGTGTGCGGCGCCGCCGAACTGATTCATGACACCCGTGACGAAACCTATACCTACAAAGGCGAAACCAC
GGTGATTCCTGCCGTCACCGGTGATTACTGCCCCGCGTGCAGCGAGGTTTTGCTAGACCGCGAGCAGGGCGACCGCTACA
GCGAACTGGTGGGCGCTTTCCAGCGCCAGGTCAACGCGGCCTTCGTCGCCCCCGGCTACATCACCGAGGTGCGCAAAAAA
CTCGCCCTCGACCAACGCGAAGCCGCCGAAATATTTGGCGGCGGCGTCAACGCTTTCTCGCGCTATGAAACCGGCAAAAC
CAAGCCCCCGCTGGCGCTGGTCAAGCTGCTGAAAGTGCTGGACCGCCACCCGGAACTGCTCGCCGAAGTGCGGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References