Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1827633..1828283 Replicon chromosome
Accession NZ_CP021644
Organism Glaesserella parasuis 29755

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag B4U42_RS09495 Protein ID WP_005710407.1
Coordinates 1827633..1827971 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag B4U42_RS09500 Protein ID WP_005710405.1
Coordinates 1827975..1828283 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4U42_RS09460 1822650..1822853 + 204 WP_005710413.1 heavy-metal-associated domain-containing protein -
B4U42_RS09465 1822858..1825005 + 2148 WP_005710411.1 cadmium-translocating P-type ATPase -
B4U42_RS09475 1825488..1826927 - 1440 WP_005710409.1 glutamate--tRNA ligase -
B4U42_RS09495 1827633..1827971 + 339 WP_005710407.1 hypothetical protein Toxin
B4U42_RS09500 1827975..1828283 + 309 WP_005710405.1 helix-turn-helix domain-containing protein Antitoxin
B4U42_RS09505 1828484..1829644 + 1161 WP_005710403.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
B4U42_RS09510 1829744..1830325 + 582 WP_005710402.1 type IV pilus biogenesis/stability protein PilW -
B4U42_RS09515 1830386..1831321 + 936 WP_005710401.1 KpsF/GutQ family sugar-phosphate isomerase -
B4U42_RS09520 1831321..1831809 + 489 WP_005710400.1 transcription elongation factor GreB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-86)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13330.35 Da        Isoelectric Point: 9.8646

>T76880 WP_005710407.1 NZ_CP021644:1827633-1827971 [Glaesserella parasuis 29755]
MNVAFVELPPFEEYRKKYLDDDSFRLLQNELLKFPDKGELIQGTEGLRKLRIVDIIRQKGKRGGARVIYYYYVRGKQVWL
FHAYNKNQQDDLSNEERVVLANTLSYLKSLVR

Download         Length: 339 bp

>T76880 NZ_CP021644:1827633-1827971 [Glaesserella parasuis 29755]
ATGAATGTCGCTTTTGTGGAGTTGCCGCCTTTTGAGGAATATAGAAAAAAGTATCTTGACGATGACTCATTTAGATTATT
ACAAAATGAGTTACTAAAATTTCCCGATAAGGGAGAGCTTATTCAAGGTACTGAGGGACTAAGAAAATTGCGTATTGTGG
ATATTATTAGACAAAAAGGAAAAAGAGGCGGAGCTAGGGTAATCTATTACTATTACGTGCGAGGGAAACAAGTTTGGTTG
TTCCACGCCTACAATAAAAACCAACAAGACGATTTATCTAATGAAGAACGTGTGGTTTTGGCGAATACATTAAGCTATTT
AAAATCTTTAGTGAGGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11539.61 Da        Isoelectric Point: 10.2919

>AT76880 WP_005710405.1 NZ_CP021644:1827975-1828283 [Glaesserella parasuis 29755]
MGKLFNELMEGMQALELHLQGKITLKTTVVEVPDPIVITPEEVKAIRQKLNLSQAVFARKLHTSVRTYQGWEQGRTKPNP
QAVLLLKMVEKSPKTFEQIASI

Download         Length: 309 bp

>AT76880 NZ_CP021644:1827975-1828283 [Glaesserella parasuis 29755]
ATGGGAAAATTATTTAATGAACTAATGGAAGGGATGCAAGCATTAGAGTTACACTTACAAGGCAAAATTACACTAAAAAC
CACTGTTGTGGAAGTTCCTGATCCGATAGTAATTACCCCTGAAGAAGTGAAAGCTATTCGTCAGAAATTAAATCTTTCAC
AAGCCGTTTTTGCTCGTAAATTACACACTTCGGTGAGAACTTATCAAGGCTGGGAGCAAGGAAGAACAAAACCTAATCCA
CAAGCGGTTTTATTATTAAAAATGGTTGAAAAATCACCAAAAACATTTGAGCAGATTGCGAGCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References