Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 3152690..3153223 Replicon chromosome
Accession NZ_CP021371
Organism Rhizobium sp. ACO-34A

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ACO34A_RS15295 Protein ID WP_099058532.1
Coordinates 3152957..3153223 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag ACO34A_RS15290 Protein ID WP_099058531.1
Coordinates 3152690..3152953 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACO34A_RS15270 3147873..3149039 - 1167 WP_099060091.1 DUF3095 domain-containing protein -
ACO34A_RS15275 3149226..3150203 - 978 WP_099058528.1 alpha/beta hydrolase -
ACO34A_RS15280 3150351..3150794 + 444 WP_099058529.1 MarR family transcriptional regulator -
ACO34A_RS15285 3150937..3152631 + 1695 WP_099058530.1 adenine deaminase -
ACO34A_RS15290 3152690..3152953 + 264 WP_099058531.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ACO34A_RS15295 3152957..3153223 + 267 WP_099058532.1 Txe/YoeB family addiction module toxin Toxin
ACO34A_RS15300 3153278..3154951 - 1674 WP_099058533.1 cation acetate symporter -
ACO34A_RS15305 3154948..3155253 - 306 WP_210422034.1 DUF485 domain-containing protein -
ACO34A_RS15310 3155478..3156287 + 810 WP_099060092.1 potassium channel family protein -
ACO34A_RS15315 3156315..3156656 - 342 WP_186363532.1 Atu4866 domain-containing protein -
ACO34A_RS30110 3156679..3156816 - 138 WP_186363366.1 hypothetical protein -
ACO34A_RS15320 3157024..3157926 + 903 WP_099058535.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10563.13 Da        Isoelectric Point: 8.0336

>T76551 WP_099058532.1 NZ_CP021371:3152957-3153223 [Rhizobium sp. ACO-34A]
VQLAFTEDAWEDYLYWQETDGKMLARINELLRDTLRHPFAGIGKPEPLKGILKGYWSRRINQEHRLVYRPMERDGVQVLV
IAQCRYHY

Download         Length: 267 bp

>T76551 NZ_CP021371:3152957-3153223 [Rhizobium sp. ACO-34A]
GTGCAGCTCGCGTTCACCGAGGACGCTTGGGAGGATTACCTGTACTGGCAGGAAACCGACGGCAAGATGCTTGCGCGCAT
CAACGAACTGCTTCGGGATACGCTGCGCCATCCTTTCGCGGGCATCGGCAAACCCGAGCCCTTGAAAGGAATCCTGAAAG
GCTATTGGTCACGGCGGATCAATCAGGAGCACCGTCTGGTCTATCGCCCCATGGAACGCGATGGCGTTCAGGTGCTCGTC
ATCGCCCAATGCCGCTATCACTATTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9539.01 Da        Isoelectric Point: 5.1409

>AT76551 WP_099058531.1 NZ_CP021371:3152690-3152953 [Rhizobium sp. ACO-34A]
MDTVFFSKARAELAGLLDKVNEDAAPVEIVRRDKPSAILIGKDEYEGMMETIHLLSSPANATRLLKAKADIEAGRFTVRD
IPLDPKG

Download         Length: 264 bp

>AT76551 NZ_CP021371:3152690-3152953 [Rhizobium sp. ACO-34A]
ATGGACACGGTTTTTTTCTCGAAGGCCCGGGCAGAACTTGCCGGCCTGCTCGACAAGGTGAACGAAGATGCGGCGCCGGT
GGAAATCGTGCGCCGCGACAAGCCGTCCGCCATCCTCATCGGCAAGGACGAATATGAGGGCATGATGGAGACCATCCACC
TGCTCTCGTCTCCGGCCAACGCCACGCGCCTGCTCAAGGCCAAGGCTGACATCGAGGCCGGCCGCTTTACGGTTCGTGAC
ATTCCTCTCGATCCCAAAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References