Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2511580..2512276 Replicon chromosome
Accession NZ_CP021359
Organism Acidovorax carolinensis strain NA2

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag CBP33_RS11765 Protein ID WP_086912711.1
Coordinates 2511980..2512276 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag CBP33_RS11760 Protein ID WP_086912710.1
Coordinates 2511580..2511978 (-) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CBP33_RS11735 2506700..2508433 - 1734 WP_086912706.1 Kef family K(+) transporter -
CBP33_RS11745 2508750..2510444 - 1695 WP_162290796.1 restriction endonuclease subunit S -
CBP33_RS11750 2510456..2510914 - 459 WP_086912708.1 hypothetical protein -
CBP33_RS11755 2510907..2511494 - 588 WP_086912709.1 nucleotidyltransferase domain-containing protein -
CBP33_RS11760 2511580..2511978 - 399 WP_086912710.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
CBP33_RS11765 2511980..2512276 - 297 WP_086912711.1 type II toxin-antitoxin system MqsR family toxin Toxin
CBP33_RS11770 2512295..2513761 - 1467 WP_086912712.1 type I restriction-modification system subunit M -
CBP33_RS11775 2513851..2516328 - 2478 WP_086912713.1 DEAD/DEAH box helicase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10894.64 Da        Isoelectric Point: 8.0518

>T76540 WP_086912711.1 NZ_CP021359:c2512276-2511980 [Acidovorax carolinensis]
MEKSTPHCKLTVVKALLQAGKFRVTRSARTGAEAMGIDFQGMLTVISALQASDFYKSMTTHADHTIWQDVYRTSSPLGDV
YLKLTVVDDLLIVSFKEL

Download         Length: 297 bp

>T76540 NZ_CP021359:c2512276-2511980 [Acidovorax carolinensis]
ATGGAAAAGAGCACACCGCATTGCAAGCTGACCGTCGTCAAGGCCCTGCTGCAAGCTGGCAAGTTTCGCGTGACGCGTTC
AGCGCGCACCGGGGCAGAGGCCATGGGCATCGACTTCCAAGGCATGCTGACCGTGATTTCGGCGCTGCAGGCGTCAGACT
TTTATAAAAGCATGACCACCCATGCCGACCACACCATCTGGCAAGACGTGTACCGCACCAGCTCGCCGCTGGGGGATGTC
TATCTCAAGTTGACCGTGGTCGATGACCTGCTGATCGTGTCTTTCAAGGAGCTATGA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14602.74 Da        Isoelectric Point: 5.2741

>AT76540 WP_086912710.1 NZ_CP021359:c2511978-2511580 [Acidovorax carolinensis]
MKCPVCGAAELIHDTRDETYTYKGESTVIPAVTGDFCPACDESLLDPAETERVMREMRAFTQQVNAAFVAPGYITEVRKK
LALDQREAAEIFGGGVNAFSRYETGKTRPPLALVKLLKVLDRHPELLAEVRS

Download         Length: 399 bp

>AT76540 NZ_CP021359:c2511978-2511580 [Acidovorax carolinensis]
ATGAAATGTCCTGTCTGCGGCGCAGCCGAACTCATTCACGATACCCGCGATGAAACCTACACCTACAAGGGTGAAAGCAC
CGTCATCCCCGCCGTGACAGGCGACTTCTGCCCGGCCTGCGATGAATCCTTGCTCGACCCGGCCGAGACCGAACGCGTCA
TGCGCGAGATGCGTGCCTTCACCCAGCAGGTCAACGCCGCCTTCGTCGCCCCCGGCTACATCACCGAGGTGCGCAAAAAG
CTCGCGCTCGACCAGCGCGAGGCCGCCGAAATTTTTGGCGGCGGCGTCAACGCCTTCTCGCGCTACGAAACCGGCAAAAC
CCGGCCCCCGCTGGCGCTGGTGAAACTGCTCAAGGTGCTCGACCGCCACCCCGAGCTGCTGGCCGAGGTGCGGTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References