76143

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2171413..2171629 Replicon chromosome
Accession NZ_CP021171
Organism Staphylococcus aureus strain CHU15-056

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag B5M25_RS11280 Protein ID WP_001802298.1
Coordinates 2171525..2171629 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2171413..2171468 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5M25_RS11260 2167619..2168284 - 666 WP_001024095.1 SDR family oxidoreductase -
B5M25_RS11265 2168436..2168756 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
B5M25_RS11270 2168758..2169735 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
B5M25_RS11275 2170001..2171092 + 1092 WP_000495669.1 hypothetical protein -
- 2171413..2171468 + 56 - - Antitoxin
B5M25_RS11280 2171525..2171629 - 105 WP_001802298.1 hypothetical protein Toxin
B5M25_RS14455 2172146..2172316 + 171 WP_001792292.1 transposase -
B5M25_RS11290 2172309..2172467 + 159 WP_001792784.1 hypothetical protein -
B5M25_RS11300 2173125..2173982 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
B5M25_RS11305 2174050..2174832 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T76143 WP_001802298.1 NZ_CP021171:c2171629-2171525 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T76143 NZ_CP021171:c2171629-2171525 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT76143 NZ_CP021171:2171413-2171468 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References