Detailed information of TA system TA075836

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 4215365..4215813
• Replicon: chromosome
• Accession: NZ_CP020964
• Organism: Xanthomonas phaseoli pv. phaseoli strain CFBP412

Toxin (Protein)

• Gene name: graT
• Uniprot ID: -
• Locus tag: XppCFBP412P_RS24050
• Protein ID: WP_201417376.1
• Coordinates: 4215673..4215813 (-)
• Length: 47 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: XppCFBP412P_RS19060
• Protein ID: WP_017156025.1
• Coordinates: 4215365..4215655 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XppCFBP412P_RS19030	4210700..4211032	+	333	WP_003482333.1	hypothetical protein	-
XppCFBP412P_RS19040	4211347..4213272	+	1926	WP_039574551.1	M61 family metallopeptidase	-
XppCFBP412P_RS24045	4213340..4213519	+	180	WP_039574549.1	hypothetical protein	-
XppCFBP412P_RS19050	4213622..4215010	-	1389	WP_039574546.1	nucleoside hydrolase	-
XppCFBP412P_RS19060	4215365..4215655	-	291	WP_017156025.1	HigA family addiction module antidote protein	Antitoxin
XppCFBP412P_RS24050	4215673..4215813	-	141	WP_201417376.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XppCFBP412P_RS19070	4216051..4218558	-	2508	WP_046834789.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (1-46)

Antitoxin

• Toxin-antitoxin system, antidote protein, HigA (1-94)

Sequences

Toxin

Protein

• Length: 47 a.a.
• Molecular weight: 5621.49 Da
• Isoelectric Point: 9.1269

>T75836 WP_201417376.1 NZ_CP020964:c4215813-4215673 [Xanthomonas phaseoli pv. phaseoli]
IPPANRLEALKGERRGQYRIRINDRWRICVRWMEGDVVQVEIIDYH

Nucleotide

• Length: 141 bp

>T75836 NZ_CP020964:c4215813-4215673 [Xanthomonas phaseoli pv. phaseoli]
ATCCCGCCCGCCAACCGGCTGGAAGCGTTGAAGGGCGAGCGGCGCGGCCAGTACCGCATCCGGATCAACGATCGATGGCG
CATCTGCGTCCGATGGATGGAAGGCGATGTGGTCCAGGTCGAAATCATCGATTACCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10387.09 Da
• Isoelectric Point: 9.0188

>AT75836 WP_017156025.1 NZ_CP020964:c4215655-4215365 [Xanthomonas phaseoli pv. phaseoli]
MTVLPNIHPGAILLEEFLQPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTFERFWLGLQADDELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT75836 NZ_CP020964:c4215655-4215365 [Xanthomonas phaseoli pv. phaseoli]
ATGACGGTCCTGCCCAATATCCACCCTGGCGCAATTCTGCTTGAGGAGTTTCTCCAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGAACCTTCGAGCGCTTCTGGCTTGGCCTGCAGGCCGACGACGAGCTGGAGCAGGCG
CATCGCGCGCTGGGCGACTTGCCGGCGCGGATCAAGCGGCTGGCGGCATGA