75811

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2153436..2153699 Replicon chromosome
Accession NZ_CP020959
Organism Staphylococcus aureus strain H489

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag B9T45_RS11220 Protein ID WP_001802298.1
Coordinates 2153595..2153699 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2153436..2153600 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9T45_RS11200 2149619..2150284 - 666 WP_001024094.1 SDR family oxidoreductase -
B9T45_RS11205 2150436..2150756 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
B9T45_RS11210 2150758..2151738 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
B9T45_RS11215 2152004..2153095 + 1092 WP_000495671.1 lytic regulatory protein -
- 2153436..2153600 + 165 - - Antitoxin
B9T45_RS11220 2153595..2153699 - 105 WP_001802298.1 hypothetical protein Toxin
B9T45_RS14400 2153860..2154343 - 484 Protein_2061 recombinase family protein -
B9T45_RS11230 2154386..2155522 - 1137 WP_000115564.1 SAP domain-containing protein -
B9T45_RS11235 2155811..2155903 + 93 WP_001790138.1 hypothetical protein -
B9T45_RS11240 2156608..2157465 - 858 WP_129950692.1 Cof-type HAD-IIB family hydrolase -
B9T45_RS11245 2157533..2158315 - 783 WP_129950693.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T75811 WP_001802298.1 NZ_CP020959:c2153699-2153595 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T75811 NZ_CP020959:c2153699-2153595 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT75811 NZ_CP020959:2153436-2153600 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References