Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2187855..2188118 Replicon chromosome
Accession NZ_CP020957
Organism Staphylococcus aureus strain C3948

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag B9T42_RS11435 Protein ID WP_001802298.1
Coordinates 2188014..2188118 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2187855..2188019 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9T42_RS11415 2184038..2184703 - 666 WP_001024094.1 SDR family oxidoreductase -
B9T42_RS11420 2184855..2185175 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
B9T42_RS11425 2185177..2186157 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
B9T42_RS11430 2186423..2187514 + 1092 WP_000495671.1 lytic regulatory protein -
- 2187855..2188019 + 165 - - Antitoxin
B9T42_RS11435 2188014..2188118 - 105 WP_001802298.1 hypothetical protein Toxin
B9T42_RS14640 2188279..2188762 - 484 Protein_2110 recombinase family protein -
B9T42_RS11445 2188805..2189942 - 1138 Protein_2111 SAP domain-containing protein -
B9T42_RS11450 2190231..2190323 + 93 WP_001790138.1 hypothetical protein -
B9T42_RS11455 2191028..2191885 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
B9T42_RS11460 2191953..2192735 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T75795 WP_001802298.1 NZ_CP020957:c2188118-2188014 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T75795 NZ_CP020957:c2188118-2188014 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT75795 NZ_CP020957:2187855-2188019 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References