75690

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 3737994..3739227 Replicon chromosome
Accession NZ_CP020918
Organism Flavobacterium faecale strain WV33

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag FFWV33_RS15655 Protein ID WP_108741771.1
Coordinates 3738301..3739227 (+) Length 309 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag FFWV33_RS15650 Protein ID WP_108741770.1
Coordinates 3737994..3738308 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFWV33_RS15625 3733267..3733659 + 393 WP_108741767.1 plasmid mobilization relaxosome protein MobC -
FFWV33_RS15630 3733647..3734939 + 1293 WP_108741768.1 relaxase/mobilization nuclease domain-containing protein -
FFWV33_RS15635 3734957..3736939 + 1983 WP_108742578.1 YWFCY domain-containing protein -
FFWV33_RS15645 3737782..3737991 + 210 WP_016989164.1 helix-turn-helix transcriptional regulator -
FFWV33_RS15650 3737994..3738308 + 315 WP_108741770.1 HipA N-terminal domain-containing protein Antitoxin
FFWV33_RS15655 3738301..3739227 + 927 WP_108741771.1 HipA domain-containing protein Toxin
FFWV33_RS15660 3739281..3740381 - 1101 WP_108741772.1 Fic family protein -
FFWV33_RS15665 3740498..3742705 - 2208 WP_108741773.1 hypothetical protein -
FFWV33_RS19340 3742708..3742854 - 147 WP_159086052.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(52-278)

Antitoxin

HipA, N-terminal subdomain 1

(3-98)


Sequences

Toxin        


Download         Length: 309 a.a.        Molecular weight: 35483.23 Da        Isoelectric Point: 8.9260

>T75690 WP_108741771.1 NZ_CP020918:3738301-3739227 [Flavobacterium faecale]
MNRCPITYELCGTDKYSVKGMRLIAPKLTHLNDLPYTAVELRQEAANRAKKLSIQGVQPKLSAAVSIVDQEFKIVDQFGT
YIIKPQNDLFSQLPENEDVTMRMAKAFGLDVPFHGMLYGKDGSLSYFIKRFDRHGKGKKWATEDFAQLTANTRDTKYRFT
MEKLIPVLDEFCSFPAIEKADFFKRILFCFVTGNEDMHLKNFSLITKNGKTTLAPIYDFLNSTIAIKNPDEEMALPLKGK
KSNLKASDFIEYYAKERLQLNEKTIATILDQMKKATPKWKELLEISFLSDEMKDKYLELLESRVIMFQ

Download         Length: 927 bp

>T75690 NZ_CP020918:3738301-3739227 [Flavobacterium faecale]
ATGAATAGATGTCCCATTACTTACGAACTGTGCGGAACAGATAAATACAGCGTAAAAGGAATGCGTCTTATTGCTCCCAA
ATTAACGCACTTAAATGATTTGCCCTATACTGCTGTCGAACTTCGTCAAGAAGCGGCTAATAGAGCCAAAAAACTATCCA
TTCAAGGGGTTCAACCAAAACTTAGTGCAGCGGTTTCTATAGTAGATCAAGAGTTTAAAATTGTAGATCAGTTTGGAACC
TACATTATCAAACCACAAAATGATTTATTCTCACAATTACCCGAAAACGAGGACGTAACCATGCGAATGGCAAAAGCATT
TGGTTTAGATGTTCCTTTTCATGGAATGCTCTACGGAAAAGATGGAAGTTTGTCTTATTTCATTAAACGTTTTGATCGCC
ACGGTAAAGGGAAAAAATGGGCAACCGAAGATTTTGCACAATTAACGGCTAATACAAGAGATACCAAATACCGCTTTACA
ATGGAAAAACTGATTCCGGTACTGGATGAATTTTGTTCTTTTCCTGCCATTGAGAAAGCAGACTTTTTTAAAAGAATACT
TTTTTGTTTTGTAACAGGTAATGAAGACATGCACTTGAAAAACTTTTCGTTAATCACCAAAAATGGTAAAACAACCCTCG
CTCCTATTTATGACTTTCTGAATTCTACCATAGCGATTAAAAATCCTGATGAAGAAATGGCACTACCCTTGAAAGGAAAA
AAGAGCAACCTAAAAGCTTCTGATTTCATAGAATATTATGCTAAAGAGAGGTTGCAACTCAACGAAAAAACAATAGCTAC
AATTCTAGATCAAATGAAAAAAGCAACTCCTAAATGGAAGGAGTTGCTTGAGATTTCTTTCCTTTCTGATGAAATGAAAG
ATAAGTATTTGGAGTTGTTGGAAAGTAGAGTTATAATGTTTCAATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11699.33 Da        Isoelectric Point: 5.1099

>AT75690 WP_108741770.1 NZ_CP020918:3737994-3738308 [Flavobacterium faecale]
MRQAIVLVHGNRAGILSEITNKEYHFEYDLDYNGEAVSLTMPTTHKKYSYNSFPPFFEGLLPEGVMLEGLLRIGKIDKKD
YFSQLIATGNDLVGSVTVKALENE

Download         Length: 315 bp

>AT75690 NZ_CP020918:3737994-3738308 [Flavobacterium faecale]
ATGAGACAAGCAATAGTATTAGTTCACGGCAATAGAGCTGGAATCCTATCCGAGATTACGAATAAAGAATATCATTTTGA
ATATGATCTTGATTATAATGGTGAGGCAGTTTCTTTAACTATGCCTACAACACATAAAAAATACAGTTACAACTCTTTTC
CTCCATTTTTTGAAGGATTACTACCCGAAGGTGTGATGCTAGAAGGATTGTTACGCATTGGCAAAATTGACAAAAAAGAT
TACTTCTCTCAACTCATTGCTACAGGAAATGATTTAGTAGGATCTGTAACGGTTAAAGCATTGGAAAATGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References