Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 14737..15394 | Replicon | plasmid pSMO-2010K-0257 |
| Accession | NZ_CP020913 | ||
| Organism | Salmonella enterica subsp. enterica serovar Montevideo str. CDC 2010K-0257 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | AW77_RS24065 | Protein ID | WP_000270043.1 |
| Coordinates | 15044..15394 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | AW77_RS24060 | Protein ID | WP_000124640.1 |
| Coordinates | 14737..15039 (-) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AW77_RS24010 | 10371..10799 | + | 429 | WP_000591076.1 | hypothetical protein | - |
| AW77_RS24015 | 10857..11216 | + | 360 | WP_000422769.1 | hypothetical protein | - |
| AW77_RS24020 | 11216..11662 | + | 447 | WP_000919343.1 | hypothetical protein | - |
| AW77_RS24025 | 11659..12177 | + | 519 | WP_000210757.1 | nitrite reductase | - |
| AW77_RS24030 | 12177..12407 | + | 231 | WP_000972665.1 | hypothetical protein | - |
| AW77_RS24035 | 12394..13251 | + | 858 | WP_001167036.1 | hypothetical protein | - |
| AW77_RS24955 | 13163..13468 | + | 306 | WP_171820680.1 | hypothetical protein | - |
| AW77_RS24045 | 13471..13998 | + | 528 | WP_001210659.1 | thermonuclease family protein | - |
| AW77_RS24050 | 14056..14328 | + | 273 | WP_001043046.1 | HU family DNA-binding protein | - |
| AW77_RS24055 | 14417..14710 | + | 294 | WP_001239998.1 | hypothetical protein | - |
| AW77_RS24060 | 14737..15039 | - | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| AW77_RS24065 | 15044..15394 | - | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| AW77_RS24070 | 15557..16105 | + | 549 | WP_001061573.1 | hypothetical protein | - |
| AW77_RS24080 | 16446..16640 | + | 195 | WP_000343597.1 | hypothetical protein | - |
| AW77_RS24085 | 16651..17022 | + | 372 | WP_000516918.1 | hypothetical protein | - |
| AW77_RS24090 | 17015..17485 | + | 471 | WP_001281821.1 | hypothetical protein | - |
| AW77_RS24095 | 17500..17835 | - | 336 | WP_000683477.1 | hypothetical protein | - |
| AW77_RS24100 | 17932..18420 | + | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| AW77_RS24105 | 18423..18920 | + | 498 | WP_000062185.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..119867 | 119867 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 17237.68 Da Isoelectric Point: 5.5500
>T75682 WP_000270043.1 NZ_CP020913:c15394-15044 [Salmonella enterica subsp. enterica serovar Montevideo str. CDC]
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FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
Download Length: 351 bp
>T75682 NZ_CP020913:c15394-15044 [Salmonella enterica subsp. enterica serovar Montevideo str. CDC]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 14882.85 Da Isoelectric Point: 5.5500
>AT75682 WP_000124640.1 NZ_CP020913:c15039-14737 [Salmonella enterica subsp. enterica serovar Montevideo str. CDC]
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Download Length: 303 bp
>AT75682 NZ_CP020913:c15039-14737 [Salmonella enterica subsp. enterica serovar Montevideo str. CDC]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|