75642

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2358764..2359368 Replicon chromosome
Accession NZ_CP020892
Organism Pseudomonas sp. M30-35

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag B9K09_RS10950 Protein ID WP_087516836.1
Coordinates 2358764..2359078 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag B9K09_RS10955 Protein ID WP_087516837.1
Coordinates 2359078..2359368 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9K09_RS10915 2354307..2354870 + 564 WP_087516829.1 hypothetical protein -
B9K09_RS10920 2355060..2355353 - 294 WP_087516830.1 hypothetical protein -
B9K09_RS10925 2355419..2356021 - 603 WP_087516831.1 hypothetical protein -
B9K09_RS10930 2356725..2357018 + 294 WP_177408723.1 transcriptional regulator -
B9K09_RS10935 2357011..2357289 + 279 WP_087516833.1 helix-turn-helix domain-containing protein -
B9K09_RS10940 2357358..2357540 - 183 WP_087516834.1 hypothetical protein -
B9K09_RS10945 2357543..2358202 - 660 WP_157699344.1 hypothetical protein -
B9K09_RS10950 2358764..2359078 + 315 WP_087516836.1 hypothetical protein Toxin
B9K09_RS10955 2359078..2359368 + 291 WP_087516837.1 helix-turn-helix domain-containing protein Antitoxin
B9K09_RS22680 2359418..2359600 - 183 WP_087516838.1 hypothetical protein -
B9K09_RS10970 2360267..2361676 - 1410 WP_087519070.1 PLP-dependent aminotransferase family protein -
B9K09_RS10975 2361742..2363157 - 1416 WP_087516839.1 cytochrome c oxidase accessory protein CcoG -
B9K09_RS10980 2363487..2363852 + 366 WP_087516840.1 CidA/LrgA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11773.71 Da        Isoelectric Point: 9.9336

>T75642 WP_087516836.1 NZ_CP020892:2358764-2359078 [Pseudomonas sp. M30-35]
MIFIETPIFTEDVRTLLSDEEYVQFQQYLVATPEAGALITQTGGLRKVRWAVQGRGKSAGVRVIYYHVTADAQIRLILIY
KKGVKDSLSAAEKAALKKLNERWM

Download         Length: 315 bp

>T75642 NZ_CP020892:2358764-2359078 [Pseudomonas sp. M30-35]
ATGATTTTTATCGAAACTCCTATTTTCACTGAAGACGTGCGCACGCTGCTTAGTGATGAGGAGTATGTACAGTTTCAACA
GTACCTTGTAGCGACGCCCGAGGCTGGTGCGCTGATTACCCAGACCGGTGGGTTGCGCAAGGTGCGCTGGGCGGTACAAG
GGCGAGGCAAAAGCGCGGGTGTGCGGGTTATTTACTACCACGTGACGGCTGATGCCCAAATTAGATTGATCTTGATCTAC
AAAAAAGGCGTGAAAGACAGCCTTAGCGCGGCGGAAAAGGCTGCGCTGAAAAAGCTAAATGAGAGGTGGATGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10931.62 Da        Isoelectric Point: 8.8061

>AT75642 WP_087516837.1 NZ_CP020892:2359078-2359368 [Pseudomonas sp. M30-35]
MEAKLFDRLLESMQQMDEIVRGERVPSREFHIDALQVKEIRKATGLTQAKFAEMIDVQLGTLRNWEQGRRDPTGPAKALL
RAIHNDPKHVLQALAG

Download         Length: 291 bp

>AT75642 NZ_CP020892:2359078-2359368 [Pseudomonas sp. M30-35]
ATGGAGGCTAAATTATTTGACCGGCTGCTCGAAAGCATGCAGCAGATGGATGAAATTGTGCGCGGAGAGCGGGTGCCCTC
CCGTGAGTTTCATATTGATGCGCTGCAGGTGAAGGAAATTCGCAAGGCCACGGGGCTGACCCAGGCTAAGTTTGCCGAAA
TGATTGATGTGCAGTTGGGCACTTTGCGCAATTGGGAGCAGGGCCGACGTGACCCAACAGGGCCAGCCAAAGCGTTGTTG
CGGGCTATTCACAACGACCCAAAGCATGTGCTTCAGGCGCTAGCTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References