Detailed information of TA system TA075453

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symER/SymE(toxin)
• Location: 3505270..3505670
• Replicon: chromosome
• Accession: NZ_CP020820
• Organism: Pantoea vagans strain FBS135

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: B9D02_RS16695
• Protein ID: WP_078804792.1
• Coordinates: 3505270..3505599 (-)
• Length: 110 a.a.

Antitoxin (RNA)

Gene name	symR
Locus tag	-
Coordinates	3505617..3505670 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B9D02_RS16660	3500982..3501566	-	585	WP_105099522.1	DJ-1/PfpI family protein	-
B9D02_RS16665	3501857..3502681	-	825	WP_197711767.1	CDP-diacylglycerol diphosphatase	-
B9D02_RS16670	3502742..3503050	-	309	WP_078804790.1	hypothetical protein	-
B9D02_RS16675	3503069..3503494	-	426	WP_078804791.1	hypothetical protein	-
B9D02_RS16680	3503491..3504192	-	702	WP_039658871.1	hypothetical protein	-
B9D02_RS16685	3504347..3504703	-	357	WP_110411681.1	hypothetical protein	-
B9D02_RS16695	3505270..3505599	-	330	WP_078804792.1	endoribonuclease SymE	Toxin
-	3505617..3505670	+	54	NuclAT_0	-	Antitoxin
-	3505617..3505670	+	54	NuclAT_0	-	Antitoxin
-	3505617..3505670	+	54	NuclAT_0	-	Antitoxin
-	3505617..3505670	+	54	NuclAT_0	-	Antitoxin
-	3505617..3505670	+	54	NuclAT_1	-	Antitoxin
-	3505617..3505670	+	54	NuclAT_1	-	Antitoxin
-	3505617..3505670	+	54	NuclAT_1	-	Antitoxin
-	3505617..3505670	+	54	NuclAT_1	-	Antitoxin
B9D02_RS16700	3505859..3505989	-	131	Protein_3221	restriction endonuclease subunit S	-
B9D02_RS16705	3506379..3507152	+	774	WP_110411682.1	type IV toxin-antitoxin system AbiEi family antitoxin	-
B9D02_RS16710	3507145..3508053	+	909	WP_110411683.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
B9D02_RS16715	3508274..3508486	+	213	WP_110411684.1	integrase core domain-containing protein	-
B9D02_RS16720	3508567..3508740	+	174	Protein_3225	DUF45 domain-containing protein	-
B9D02_RS16725	3508779..3510260	-	1482	WP_078804795.1	N-6 DNA methylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3503491..3512569	9078

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 12067.89 Da
• Isoelectric Point: 9.1097

>T75453 WP_078804792.1 NZ_CP020820:c3505599-3505270 [Pantoea vagans]
MTDAHSIAQLSEPEVSPSNNRQLTVGYASRYPDYSRIPAITMKGQWLEAAGFVTGTAVEVKVMEGCIVLTARQESELVQS
LRQVCKLSARKQKQVQEFIQVISGKQKVV

Nucleotide

• Length: 330 bp

>T75453 NZ_CP020820:c3505599-3505270 [Pantoea vagans]
ATGACTGACGCCCATTCTATTGCACAACTCTCTGAACCAGAAGTCTCGCCTTCAAATAACCGCCAGCTGACGGTTGGCTA
CGCGAGCCGCTATCCGGATTACAGCCGGATTCCCGCCATCACTATGAAAGGACAATGGCTGGAAGCAGCCGGCTTTGTCA
CTGGCACAGCCGTAGAGGTAAAGGTAATGGAAGGCTGTATTGTGCTCACTGCCCGGCAGGAGAGCGAACTAGTGCAGTCG
CTGCGCCAGGTATGCAAGCTGTCGGCGCGGAAACAAAAGCAGGTTCAGGAGTTTATTCAGGTTATATCCGGTAAACAGAA
AGTCGTTTGA

Antitoxin

Nucleotide

• Length: 54 bp

>AT75453 NZ_CP020820:3505617-3505670 [Pantoea vagans]
AATAGTGATTGTGATTAGCGGCGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin