75405

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe(toxin)
Location 3181829..3182348 Replicon chromosome
Accession NZ_CP020771
Organism Microcystis aeruginosa PCC 7806SL

Toxin (Protein)


Gene name yoeB Uniprot ID I4GN90
Locus tag BH695_RS15685 Protein ID WP_002746068.1
Coordinates 3181829..3182095 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1X9LF82
Locus tag BH695_RS15690 Protein ID WP_002746071.1
Coordinates 3182088..3182348 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BH695_RS27220 3177614..3177757 + 144 WP_002746053.1 hypothetical protein -
BH695_RS15675 3177809..3180196 - 2388 WP_002746055.1 ATP-dependent Clp protease ATP-binding subunit -
BH695_RS15680 3180699..3181184 + 486 WP_194032470.1 hypothetical protein -
BH695_RS15685 3181829..3182095 - 267 WP_002746068.1 Txe/YoeB family addiction module toxin Toxin
BH695_RS15690 3182088..3182348 - 261 WP_002746071.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BH695_RS15705 3183635..3184591 + 957 WP_002742982.1 ribonuclease Z -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10588.24 Da        Isoelectric Point: 9.9458

>T75405 WP_002746068.1 NZ_CP020771:c3182095-3181829 [Microcystis aeruginosa PCC 7806SL]
MDNWQLVFTKQAKKDAEKLARTWLAKQANELLNILKSNPYQSYPVYEKLSGDLASYYSRRINIQHRLVYQVIPEEKVVKV
IRMWTHYE

Download         Length: 267 bp

>T75405 NZ_CP020771:c3182095-3181829 [Microcystis aeruginosa PCC 7806SL]
ATGGATAATTGGCAGTTGGTTTTTACCAAACAAGCGAAAAAAGATGCTGAAAAGCTTGCTCGTACTTGGTTGGCAAAACA
AGCTAACGAGTTATTAAATATTCTTAAGTCAAATCCGTATCAATCTTATCCTGTTTATGAGAAACTCAGTGGCGATTTAG
CGAGCTATTATTCCAGACGTATTAATATTCAGCATCGTTTGGTTTATCAGGTTATTCCAGAAGAGAAGGTTGTCAAAGTT
ATACGGATGTGGACTCATTATGAATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9406.52 Da        Isoelectric Point: 3.9365

>AT75405 WP_002746071.1 NZ_CP020771:c3182348-3182088 [Microcystis aeruginosa PCC 7806SL]
MKIVTVTEAKEQIDELVNDTNDNHQPILLSGTKKNAILIAEEDWNSIQETLHLYSIPGMVDSIIEGGNTSIEDCVDEAGI
RAILNG

Download         Length: 261 bp

>AT75405 NZ_CP020771:c3182348-3182088 [Microcystis aeruginosa PCC 7806SL]
ATGAAAATTGTTACTGTTACTGAAGCCAAAGAACAAATTGATGAATTAGTGAATGATACCAATGATAATCATCAACCGAT
TTTGTTATCTGGTACGAAAAAGAATGCTATTTTAATTGCTGAGGAAGATTGGAACTCTATTCAAGAAACGCTTCATTTGT
ATTCTATTCCTGGTATGGTAGATTCAATTATTGAAGGTGGCAACACTTCTATTGAAGATTGTGTGGATGAGGCGGGTATC
AGAGCAATTTTAAATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1X9LC23

Antitoxin

Source ID Structure
AlphaFold DB A0A1X9LF82

References