Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2482290..2482474 Replicon chromosome
Accession NZ_CP020741
Organism Staphylococcus aureus strain HZW450

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag B7437_RS12760 Protein ID WP_000482647.1
Coordinates 2482367..2482474 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2482290..2482350 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7437_RS12740 2477800..2477967 - 168 WP_031845053.1 hypothetical protein -
B7437_RS12750 2478198..2479931 - 1734 WP_000488493.1 ABC transporter ATP-binding protein/permease -
B7437_RS12755 2480007..2481719 - 1713 WP_001064821.1 ABC transporter ATP-binding protein/permease -
B7437_RS14665 2482173..2482340 - 168 WP_000301893.1 hypothetical protein -
- 2482290..2482350 + 61 - - Antitoxin
B7437_RS12760 2482367..2482474 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
B7437_RS12765 2482607..2482993 - 387 WP_000779353.1 flippase GtxA -
B7437_RS12770 2483261..2484403 + 1143 WP_001176863.1 glycerate kinase -
B7437_RS12775 2484463..2485122 + 660 WP_000831298.1 membrane protein -
B7437_RS12780 2485305..2486516 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
B7437_RS12785 2486639..2487112 - 474 WP_000456483.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T75363 WP_000482647.1 NZ_CP020741:c2482474-2482367 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T75363 NZ_CP020741:c2482474-2482367 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT75363 NZ_CP020741:2482290-2482350 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References