Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2194837..2195100 Replicon chromosome
Accession NZ_CP020741
Organism Staphylococcus aureus strain HZW450

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag B7437_RS11225 Protein ID WP_001802298.1
Coordinates 2194996..2195100 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2194837..2195001 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7437_RS11205 2191074..2191739 - 666 WP_001024088.1 SDR family oxidoreductase -
B7437_RS11210 2191891..2192211 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
B7437_RS11215 2192213..2193190 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
B7437_RS11220 2193456..2194547 + 1092 WP_000495695.1 hypothetical protein -
- 2194837..2195001 + 165 - - Antitoxin
B7437_RS11225 2194996..2195100 - 105 WP_001802298.1 hypothetical protein Toxin
B7437_RS14580 2195261..2195744 - 484 Protein_2084 recombinase family protein -
B7437_RS11235 2195787..2196923 - 1137 Protein_2085 SAP domain-containing protein -
B7437_RS11240 2197212..2197304 + 93 WP_031844941.1 hypothetical protein -
B7437_RS11245 2197999..2198856 - 858 WP_000370919.1 Cof-type HAD-IIB family hydrolase -
B7437_RS11250 2198924..2199706 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T75362 WP_001802298.1 NZ_CP020741:c2195100-2194996 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T75362 NZ_CP020741:c2195100-2194996 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT75362 NZ_CP020741:2194837-2195001 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References