Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1116290..1116797 Replicon chromosome
Accession NZ_CP020715
Organism Cnuibacter physcomitrellae strain XA(T)

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag B5808_RS05235 Protein ID WP_085018832.1
Coordinates 1116290..1116556 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag B5808_RS05240 Protein ID WP_085018833.1
Coordinates 1116549..1116797 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5808_RS05205 1111811..1113178 + 1368 WP_085018827.1 serine hydroxymethyltransferase -
B5808_RS05210 1113172..1114053 + 882 WP_085018828.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
B5808_RS05215 1114205..1115029 + 825 WP_085021355.1 aldose 1-epimerase family protein -
B5808_RS05220 1115134..1115469 + 336 WP_085018829.1 hypothetical protein -
B5808_RS05225 1115597..1115911 + 315 WP_085018830.1 hypothetical protein -
B5808_RS05230 1115908..1116258 - 351 WP_085018831.1 hypothetical protein -
B5808_RS05235 1116290..1116556 - 267 WP_085018832.1 Txe/YoeB family addiction module toxin Toxin
B5808_RS05240 1116549..1116797 - 249 WP_085018833.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
B5808_RS05245 1116879..1117082 - 204 WP_085018834.1 hypothetical protein -
B5808_RS05255 1118000..1118629 + 630 WP_085018835.1 DNA-directed RNA polymerase subunit beta -
B5808_RS05260 1118793..1119572 - 780 WP_085018836.1 phosphate ABC transporter ATP-binding protein -
B5808_RS05265 1119605..1120702 - 1098 WP_085018837.1 phosphate ABC transporter permease PstA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10379.78 Da        Isoelectric Point: 7.1994

>T75343 WP_085018832.1 NZ_CP020715:c1116556-1116290 [Cnuibacter physcomitrellae]
VSERKLAWTAGAWQDYLYWQNQDRRTLRRINLLIDDVLRDDPFDGIGKPEPLKHALAGAWSRRIDEANRLVYLVDGDLVV
ILQARYHY

Download         Length: 267 bp

>T75343 NZ_CP020715:c1116556-1116290 [Cnuibacter physcomitrellae]
GTGAGTGAGCGCAAGCTCGCTTGGACGGCCGGTGCCTGGCAGGACTACCTCTACTGGCAGAACCAAGACCGACGTACGCT
CCGCCGCATCAACCTGCTGATCGACGACGTCCTGCGGGACGATCCGTTCGACGGCATCGGCAAGCCGGAACCCCTGAAGC
ACGCCCTCGCCGGGGCATGGTCGCGGCGGATCGACGAGGCCAACCGTCTCGTCTACCTCGTCGACGGAGACCTCGTGGTC
ATCCTGCAGGCGCGGTACCACTACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9200.34 Da        Isoelectric Point: 4.5098

>AT75343 WP_085018833.1 NZ_CP020715:c1116797-1116549 [Cnuibacter physcomitrellae]
MAITASEARSDLFGLIERVNLDQTEIEITSKRGSAVLMSKDEYDALVETTYLLRSPKNARRLLEAMDSARSGDVVEHDLT
RE

Download         Length: 249 bp

>AT75343 NZ_CP020715:c1116797-1116549 [Cnuibacter physcomitrellae]
ATGGCCATCACGGCGAGCGAGGCGCGCAGCGACCTCTTTGGTCTCATCGAGCGCGTGAACCTCGACCAGACGGAGATCGA
GATCACGTCCAAGCGCGGATCGGCGGTGCTCATGTCGAAGGACGAATACGACGCGCTGGTCGAGACGACCTACCTCCTCC
GGTCGCCCAAGAACGCTCGACGTCTTCTCGAGGCCATGGACAGCGCACGTTCCGGCGACGTCGTGGAGCACGACCTGACC
CGTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References