Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2624341..2624619 Replicon chromosome
Accession NZ_CP020714
Organism Staphylococcus aureus strain K18

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag B7474_RS13750 Protein ID WP_001802298.1
Coordinates 2624341..2624445 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2624441..2624619 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7474_RS13725 2621138..2621920 + 783 WP_000908180.1 ABC transporter ATP-binding protein -
B7474_RS13730 2621988..2622845 + 858 WP_000370930.1 Cof-type HAD-IIB family hydrolase -
B7474_RS13740 2623503..2623661 - 159 WP_001792784.1 hypothetical protein -
B7474_RS13750 2624341..2624445 + 105 WP_001802298.1 hypothetical protein Toxin
- 2624441..2624619 - 179 - - Antitoxin
B7474_RS13755 2624887..2625978 - 1092 WP_000495681.1 hypothetical protein -
B7474_RS13760 2626244..2627224 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
B7474_RS13765 2627226..2627546 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
B7474_RS13770 2627698..2628363 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T75339 WP_001802298.1 NZ_CP020714:2624341-2624445 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T75339 NZ_CP020714:2624341-2624445 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT75339 NZ_CP020714:c2624619-2624441 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References