Detailed information of TA system TA075332

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1654540..1654720
• Replicon: chromosome
• Accession: NZ_CP020714
• Organism: Staphylococcus aureus strain K18

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: B7474_RS14315
• Protein ID: WP_001801861.1
• Coordinates: 1654625..1654720 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1654540..1654597 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B7474_RS08510	1650141..1651406	+	1266	WP_000072555.1	restriction endonuclease subunit S	-
B7474_RS08515	1651445..1652299	+	855	WP_001069960.1	DNA adenine methylase	-
B7474_RS08520	1652277..1653974	+	1698	WP_101766563.1	hypothetical protein	-
-	1654540..1654597	+	58	-	-	Antitoxin
B7474_RS14315	1654625..1654720	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
B7474_RS08530	1655171..1655617	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
B7474_RS08535	1655801..1656357	+	557	Protein_1581	ImmA/IrrE family metallo-endopeptidase	-
B7474_RS08540	1656489..1657241	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
B7474_RS08545	1657268..1658011	-	744	WP_199559051.1	exotoxin	-
B7474_RS08550	1658038..1658664	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	1633258..1661222	27964

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (3-108)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T75332 WP_001801861.1 NZ_CP020714:c1654720-1654625 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T75332 NZ_CP020714:c1654720-1654625 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT75332 NZ_CP020714:1654540-1654597 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin