Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1161719..1161903 Replicon chromosome
Accession NZ_CP020714
Organism Staphylococcus aureus strain K18

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag B7474_RS05810 Protein ID WP_000482647.1
Coordinates 1161719..1161826 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1161843..1161903 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7474_RS05785 1157091..1157564 + 474 WP_000456489.1 GyrI-like domain-containing protein -
B7474_RS05790 1157687..1158898 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
B7474_RS05795 1159080..1159739 - 660 WP_000831298.1 membrane protein -
B7474_RS05800 1159799..1160941 - 1143 WP_001176863.1 glycerate kinase -
B7474_RS05805 1161199..1161585 + 387 WP_000779360.1 flippase GtxA -
B7474_RS05810 1161719..1161826 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1161843..1161903 - 61 - - Antitoxin
B7474_RS05820 1162454..1164217 + 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
B7474_RS05825 1164242..1165975 + 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
B7474_RS05835 1166206..1166373 + 168 WP_001790576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T75328 WP_000482647.1 NZ_CP020714:1161719-1161826 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T75328 NZ_CP020714:1161719-1161826 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT75328 NZ_CP020714:c1161903-1161843 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References