Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1011530..1011710 Replicon chromosome
Accession NZ_CP020713
Organism Staphylococcus aureus strain K17

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag B7473_RS14285 Protein ID WP_001801861.1
Coordinates 1011615..1011710 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1011530..1011587 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7473_RS05230 1007131..1008396 + 1266 WP_000072555.1 restriction endonuclease subunit S -
B7473_RS05235 1008435..1009289 + 855 WP_001069960.1 DNA adenine methylase -
B7473_RS05240 1009267..1010964 + 1698 WP_101766563.1 hypothetical protein -
- 1011530..1011587 + 58 - - Antitoxin
B7473_RS14285 1011615..1011710 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
B7473_RS05250 1012161..1012607 + 447 WP_000747805.1 DUF1433 domain-containing protein -
B7473_RS05255 1012791..1013347 + 557 Protein_998 ImmA/IrrE family metallo-endopeptidase -
B7473_RS05260 1013479..1014231 - 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
B7473_RS05265 1014258..1015001 - 744 WP_199559051.1 exotoxin -
B7473_RS05270 1015028..1015654 - 627 WP_000669028.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 990248..1018211 27963


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T75318 WP_001801861.1 NZ_CP020713:c1011710-1011615 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T75318 NZ_CP020713:c1011710-1011615 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT75318 NZ_CP020713:1011530-1011587 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References