Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2659356..2659553 Replicon chromosome
Accession NZ_CP020656
Organism Staphylococcus aureus strain K5

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag B7R57_RS13960 Protein ID WP_001802298.1
Coordinates 2659449..2659553 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2659356..2659394 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7R57_RS13940 2655531..2656196 - 666 WP_001024095.1 SDR family oxidoreductase -
B7R57_RS13945 2656348..2656668 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
B7R57_RS13950 2656670..2657650 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
B7R57_RS13955 2657916..2659007 + 1092 WP_000495681.1 hypothetical protein -
- 2659356..2659394 + 39 - - Antitoxin
B7R57_RS13960 2659449..2659553 - 105 WP_001802298.1 hypothetical protein Toxin
B7R57_RS14245 2660070..2660240 + 171 WP_001792292.1 transposase -
B7R57_RS13970 2660233..2660391 + 159 WP_001792784.1 hypothetical protein -
B7R57_RS13980 2661049..2661906 - 858 WP_000370930.1 Cof-type HAD-IIB family hydrolase -
B7R57_RS13985 2661974..2662756 - 783 WP_000908180.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T75258 WP_001802298.1 NZ_CP020656:c2659553-2659449 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T75258 NZ_CP020656:c2659553-2659449 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT75258 NZ_CP020656:2659356-2659394 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References