75253

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2416923..2417103 Replicon chromosome
Accession NZ_CP020656
Organism Staphylococcus aureus strain K5

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag B7R57_RS14240 Protein ID WP_001801861.1
Coordinates 2417008..2417103 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2416923..2416980 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7R57_RS12655 2412524..2413789 + 1266 WP_000072555.1 restriction endonuclease subunit S -
B7R57_RS12660 2413828..2414682 + 855 WP_001069960.1 DNA adenine methylase -
B7R57_RS12665 2414660..2416357 + 1698 WP_101766563.1 hypothetical protein -
- 2416923..2416980 + 58 - - Antitoxin
B7R57_RS14240 2417008..2417103 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
B7R57_RS12675 2417554..2418000 + 447 WP_000747805.1 DUF1433 domain-containing protein -
B7R57_RS12680 2418184..2418740 + 557 Protein_2380 ImmA/IrrE family metallo-endopeptidase -
B7R57_RS12685 2418872..2419624 - 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
B7R57_RS12690 2419651..2420334 - 684 WP_158294611.1 exotoxin -
B7R57_RS12695 2420421..2421047 - 627 WP_000669028.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 2395641..2423605 27964


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T75253 WP_001801861.1 NZ_CP020656:c2417103-2417008 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T75253 NZ_CP020656:c2417103-2417008 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT75253 NZ_CP020656:2416923-2416980 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References