Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1476942..1477126 Replicon chromosome
Accession NZ_CP020656
Organism Staphylococcus aureus strain K5

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag B7R57_RS07745 Protein ID WP_000482647.1
Coordinates 1477019..1477126 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1476942..1477002 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7R57_RS07720 1472472..1472639 - 168 WP_001790576.1 hypothetical protein -
B7R57_RS07730 1472870..1474603 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
B7R57_RS07735 1474628..1476391 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
- 1476942..1477002 + 61 - - Antitoxin
B7R57_RS07745 1477019..1477126 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
B7R57_RS07750 1477260..1477646 - 387 WP_000779360.1 flippase GtxA -
B7R57_RS07755 1477904..1479046 + 1143 WP_001176863.1 glycerate kinase -
B7R57_RS07760 1479106..1479765 + 660 WP_000831298.1 membrane protein -
B7R57_RS07765 1479947..1481158 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
B7R57_RS07770 1481281..1481754 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T75248 WP_000482647.1 NZ_CP020656:c1477126-1477019 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T75248 NZ_CP020656:c1477126-1477019 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT75248 NZ_CP020656:1476942-1477002 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References