75198

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2266418..2266681 Replicon chromosome
Accession NZ_CP020619
Organism Staphylococcus aureus strain JE2

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag B7H15_RS11920 Protein ID WP_001802298.1
Coordinates 2266577..2266681 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2266418..2266582 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7H15_RS11900 2262601..2263266 - 666 WP_001024094.1 SDR family oxidoreductase -
B7H15_RS11905 2263418..2263738 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
B7H15_RS11910 2263740..2264720 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
B7H15_RS11915 2264986..2266077 + 1092 WP_000495671.1 lytic regulatory protein -
- 2266418..2266582 + 165 - - Antitoxin
B7H15_RS11920 2266577..2266681 - 105 WP_001802298.1 hypothetical protein Toxin
B7H15_RS15375 2266842..2267325 - 484 Protein_2196 recombinase family protein -
B7H15_RS11930 2267368..2268504 - 1137 WP_000115564.1 SAP domain-containing protein -
B7H15_RS11935 2268793..2268885 + 93 WP_001790138.1 hypothetical protein -
B7H15_RS11940 2269590..2270447 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
B7H15_RS11945 2270515..2271297 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T75198 WP_001802298.1 NZ_CP020619:c2266681-2266577 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T75198 NZ_CP020619:c2266681-2266577 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT75198 NZ_CP020619:2266418-2266582 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References