Detailed information of TA system TA075105

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 3860984..3861206
• Replicon: chromosome
• Accession: NZ_CP020545
• Organism: Escherichia coli strain ZJ3920

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: B6V57_RS28500
• Protein ID: WP_001295224.1
• Coordinates: 3860984..3861091 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	3861140..3861206 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B6V57_RS20100	3856519..3856707	-	189	WP_001063314.1	YhjR family protein	-
B6V57_RS20105	3856980..3858551	+	1572	WP_001204957.1	cellulose biosynthesis protein BcsE	-
B6V57_RS20110	3858548..3858739	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
B6V57_RS20115	3858736..3860415	+	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
B6V57_RS20120	3860501..3860608	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
B6V57_RS28500	3860984..3861091	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	3861140..3861206	+	67	-	-	Antitoxin
B6V57_RS20140	3861466..3861573	-	108	WP_000170745.1	type I toxin-antitoxin system toxin Ldr family protein	-
B6V57_RS20150	3862049..3863320	+	1272	WP_001332306.1	amino acid permease	-
B6V57_RS20155	3863350..3864354	-	1005	WP_148123951.1	dipeptide ABC transporter ATP-binding subunit DppF	-
B6V57_RS20160	3864351..3865334	-	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T75105 WP_001295224.1 NZ_CP020545:c3861091-3860984 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T75105 NZ_CP020545:c3861091-3860984 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCACGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 67 bp

>AT75105 NZ_CP020545:3861140-3861206 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin