Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2258874..2259090 Replicon chromosome
Accession NZ_CP020467
Organism Staphylococcus aureus strain CFSAN007896

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag AB477_RS11655 Protein ID WP_073392962.1
Coordinates 2258986..2259090 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2258874..2258929 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB477_RS11635 2253967..2254287 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AB477_RS11640 2254289..2255269 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
AB477_RS11645 2255535..2256626 + 1092 WP_000495684.1 hypothetical protein -
AB477_RS11650 2256914..2258560 + 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
- 2258874..2258929 + 56 - - Antitoxin
AB477_RS11655 2258986..2259090 - 105 WP_073392962.1 hypothetical protein Toxin
AB477_RS11665 2259770..2259928 + 159 WP_001792784.1 hypothetical protein -
AB477_RS11675 2260587..2261444 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
AB477_RS11680 2261512..2262294 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2256914..2258560 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T74722 WP_073392962.1 NZ_CP020467:c2259090-2258986 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T74722 NZ_CP020467:c2259090-2258986 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT74722 NZ_CP020467:2258874-2258929 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References