Detailed information of TA system TA074714

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1913227..1913407
• Replicon: chromosome
• Accession: NZ_CP020467
• Organism: Staphylococcus aureus strain CFSAN007896

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: AB477_RS09510
• Protein ID: WP_001801861.1
• Coordinates: 1913227..1913322 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1913350..1913407 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AB477_RS09470	1908370..1908996	+	627	WP_000669038.1	hypothetical protein	-
AB477_RS09475	1909037..1909381	+	345	WP_000627550.1	DUF3969 family protein	-
AB477_RS09480	1909479..1910051	+	573	WP_000414222.1	hypothetical protein	-
AB477_RS09485	1910200..1911141	-	942	WP_001794355.1	FRG domain-containing protein	-
AB477_RS09490	1911158..1911568	-	411	WP_107375236.1	hypothetical protein	-
AB477_RS09495	1911568..1912137	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
AB477_RS09500	1912330..1912776	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
AB477_RS09510	1913227..1913322	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1913350..1913407	-	58	-	-	Antitoxin
AB477_RS09515	1913445..1913546	+	102	WP_001791232.1	hypothetical protein	-
AB477_RS09520	1913721..1914164	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
AB477_RS09525	1914164..1914607	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
AB477_RS09530	1914607..1915049	-	443	Protein_1802	DUF1433 domain-containing protein	-
AB477_RS09535	1915574..1917994	+	2421	WP_000182553.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T74714 WP_001801861.1 NZ_CP020467:1913227-1913322 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T74714 NZ_CP020467:1913227-1913322 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT74714 NZ_CP020467:c1913407-1913350 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin