Detailed information of TA system TA074709

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 995837..996086
• Replicon: chromosome
• Accession: NZ_CP020467
• Organism: Staphylococcus aureus strain CFSAN007896

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: AB477_RS04910
• Protein ID: WP_000623369.1
• Coordinates: 995837..995944 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	995939..996086 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AB477_RS04885	992510..993079	-	570	WP_000287265.1	competence protein ComK	-
AB477_RS04890	993289..993507	+	219	WP_000876825.1	IDEAL domain-containing protein	-
AB477_RS04895	993588..994574	-	987	WP_107375205.1	lipoate--protein ligase	-
AB477_RS04900	994773..994949	+	177	WP_000214898.1	YkvS family protein	-
AB477_RS04905	994964..995566	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
AB477_RS04910	995837..995944	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	995939..996086	-	148	-	-	Antitoxin
AB477_RS04915	996483..996584	+	102	WP_001790623.1	hypothetical protein	-
AB477_RS04920	996594..996866	+	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
AB477_RS04925	996910..998874	+	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
AB477_RS04930	998877..999197	+	321	WP_000873929.1	YxeA family protein	-
AB477_RS04935	999194..999835	+	642	WP_000571191.1	ABC transporter ATP-binding protein	-
AB477_RS04940	999923..1000213	-	291	WP_001791476.1	hypothetical protein	-
AB477_RS04945	1000554..1000841	+	288	WP_000410718.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T74709 WP_000623369.1 NZ_CP020467:995837-995944 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T74709 NZ_CP020467:995837-995944 [Staphylococcus aureus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT74709 NZ_CP020467:c996086-995939 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGATATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin