Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-DinJ |
Location | 2579604..2580147 | Replicon | chromosome |
Accession | NZ_CP020464 | ||
Organism | Lacticaseibacillus rhamnosus strain Pen |
Toxin (Protein)
Gene name | yafQ | Uniprot ID | - |
Locus tag | BVH57_RS13000 | Protein ID | WP_005709630.1 |
Coordinates | 2579860..2580147 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | - |
Locus tag | BVH57_RS12995 | Protein ID | WP_005714439.1 |
Coordinates | 2579604..2579876 (+) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BVH57_RS12975 | 2575203..2576303 | - | 1101 | WP_005709638.1 | metalloregulator ArsR/SmtB family transcription factor | - |
BVH57_RS12980 | 2576416..2577789 | + | 1374 | WP_005714442.1 | MFS transporter | - |
BVH57_RS12985 | 2577952..2579115 | - | 1164 | WP_005709634.1 | MFS transporter | - |
BVH57_RS12990 | 2579197..2579490 | - | 294 | WP_005684269.1 | metalloregulator ArsR/SmtB family transcription factor | - |
BVH57_RS12995 | 2579604..2579876 | + | 273 | WP_005714439.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
BVH57_RS13000 | 2579860..2580147 | + | 288 | WP_005709630.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
BVH57_RS13005 | 2580371..2581780 | + | 1410 | WP_005714438.1 | 3'-5' exonuclease | - |
BVH57_RS13010 | 2581998..2582177 | + | 180 | WP_005709626.1 | hypothetical protein | - |
BVH57_RS13015 | 2582288..2582716 | + | 429 | WP_005714437.1 | OsmC family protein | - |
BVH57_RS13020 | 2582910..2583929 | + | 1020 | WP_005709622.1 | dihydroxyacetone kinase subunit DhaK | - |
BVH57_RS13025 | 2583916..2584497 | + | 582 | WP_005709619.1 | dihydroxyacetone kinase subunit L | - |
BVH57_RS13030 | 2584531..2584899 | + | 369 | WP_005686376.1 | PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 10888.77 Da Isoelectric Point: 10.9032
>T74702 WP_005709630.1 NZ_CP020464:2579860-2580147 [Lacticaseibacillus rhamnosus]
MMLTINRTRTFKRQFKHLLRQGKDMTKLATAIDTLQRQDRVKLASLHDHALKGAHSGERALRVAPDWLLVYKVDAEALIL
MLLATGTHRDTLNIE
MMLTINRTRTFKRQFKHLLRQGKDMTKLATAIDTLQRQDRVKLASLHDHALKGAHSGERALRVAPDWLLVYKVDAEALIL
MLLATGTHRDTLNIE
Download Length: 288 bp
>T74702 NZ_CP020464:2579860-2580147 [Lacticaseibacillus rhamnosus]
ATGATGTTGACGATTAATCGCACGCGCACTTTCAAACGACAATTTAAACATCTTCTTAGGCAAGGTAAAGATATGACGAA
ACTTGCAACTGCAATTGATACTTTGCAGCGTCAAGATCGTGTAAAATTAGCTTCTTTACACGACCATGCTTTAAAGGGTG
CTCACAGCGGCGAACGAGCATTGCGTGTTGCTCCTGATTGGCTTCTCGTTTATAAAGTCGATGCTGAAGCGTTAATTTTA
ATGCTTCTTGCAACAGGCACACACCGCGATACATTGAACATTGAGTAA
ATGATGTTGACGATTAATCGCACGCGCACTTTCAAACGACAATTTAAACATCTTCTTAGGCAAGGTAAAGATATGACGAA
ACTTGCAACTGCAATTGATACTTTGCAGCGTCAAGATCGTGTAAAATTAGCTTCTTTACACGACCATGCTTTAAAGGGTG
CTCACAGCGGCGAACGAGCATTGCGTGTTGCTCCTGATTGGCTTCTCGTTTATAAAGTCGATGCTGAAGCGTTAATTTTA
ATGCTTCTTGCAACAGGCACACACCGCGATACATTGAACATTGAGTAA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10073.49 Da Isoelectric Point: 5.1154
>AT74702 WP_005714439.1 NZ_CP020464:2579604-2579876 [Lacticaseibacillus rhamnosus]
METKSRISVRIDTKTKERALHVLNSMGLDMSSAINMYLKRIGDTGELPFTPEMSFADQLQAAEADVKAGRTKSFKTVDAL
MKDLYNDVDD
METKSRISVRIDTKTKERALHVLNSMGLDMSSAINMYLKRIGDTGELPFTPEMSFADQLQAAEADVKAGRTKSFKTVDAL
MKDLYNDVDD
Download Length: 273 bp
>AT74702 NZ_CP020464:2579604-2579876 [Lacticaseibacillus rhamnosus]
ATGGAAACAAAATCCCGTATCAGCGTGCGAATTGATACCAAAACCAAAGAACGGGCTCTCCATGTCCTCAATAGCATGGG
ACTAGATATGTCCTCAGCTATTAACATGTATTTGAAACGCATTGGTGACACTGGTGAGTTGCCATTTACACCTGAAATGT
CGTTCGCCGATCAGCTTCAAGCTGCAGAAGCTGATGTTAAAGCGGGACGAACTAAGAGCTTCAAGACCGTTGATGCCCTG
ATGAAGGATTTATACAATGATGTTGACGATTAA
ATGGAAACAAAATCCCGTATCAGCGTGCGAATTGATACCAAAACCAAAGAACGGGCTCTCCATGTCCTCAATAGCATGGG
ACTAGATATGTCCTCAGCTATTAACATGTATTTGAAACGCATTGGTGACACTGGTGAGTTGCCATTTACACCTGAAATGT
CGTTCGCCGATCAGCTTCAAGCTGCAGAAGCTGATGTTAAAGCGGGACGAACTAAGAGCTTCAAGACCGTTGATGCCCTG
ATGAAGGATTTATACAATGATGTTGACGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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