Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2396465..2396649 Replicon chromosome
Accession NZ_CP020354
Organism Staphylococcus aureus strain FORC59

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag FORC59_RS12350 Protein ID WP_072467491.1
Coordinates 2396542..2396649 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2396465..2396525 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC59_RS12325 2392033..2392200 - 168 WP_031866196.1 hypothetical protein -
FORC59_RS12335 2392431..2394164 - 1734 WP_000486502.1 ABC transporter ATP-binding protein/permease -
FORC59_RS12340 2394189..2395952 - 1764 WP_106669557.1 ABC transporter ATP-binding protein/permease -
- 2396465..2396525 + 61 - - Antitoxin
FORC59_RS12350 2396542..2396649 - 108 WP_072467491.1 type I toxin-antitoxin system Fst family toxin Toxin
FORC59_RS12355 2396783..2397169 - 387 WP_000779348.1 flippase GtxA -
FORC59_RS12360 2397426..2398568 + 1143 WP_001176873.1 glycerate kinase -
FORC59_RS12365 2398628..2399287 + 660 WP_000831298.1 membrane protein -
FORC59_RS12370 2399469..2400680 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
FORC59_RS12375 2400803..2401276 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3944.67 Da        Isoelectric Point: 10.4934

>T74366 WP_072467491.1 NZ_CP020354:c2396649-2396542 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Download         Length: 108 bp

>T74366 NZ_CP020354:c2396649-2396542 [Staphylococcus aureus]
ATCTTCAATTTATTAATTGACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCAAATTGGTTACGAAC
GCGCAGCAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT74366 NZ_CP020354:2396465-2396525 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References