Detailed information of TA system TA074357

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1826053..1826233
• Replicon: chromosome
• Accession: NZ_CP020354
• Organism: Staphylococcus aureus strain FORC59

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FORC59_RS09085
• Protein ID: WP_001801861.1
• Coordinates: 1826053..1826148 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1826176..1826233 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FORC59_RS09045	1821094..1821720	+	627	WP_000669019.1	hypothetical protein	-
FORC59_RS09050	1821761..1822102	+	342	WP_049311638.1	DUF3969 family protein	-
FORC59_RS14130	1822203..1822775	+	573	Protein_1699	hypothetical protein	-
FORC59_RS09055	1822973..1823530	-	558	WP_000864138.1	ImmA/IrrE family metallo-endopeptidase	-
FORC59_RS09065	1823901..1824077	-	177	WP_000375476.1	hypothetical protein	-
FORC59_RS09070	1824088..1824471	-	384	WP_000070811.1	hypothetical protein	-
FORC59_RS09075	1825156..1825602	-	447	WP_000747802.1	DUF1433 domain-containing protein	-
FORC59_RS09085	1826053..1826148	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1826176..1826233	-	58	-	-	Antitoxin
FORC59_RS09090	1826271..1826372	+	102	WP_001791232.1	hypothetical protein	-
FORC59_RS09095	1826350..1826532	-	183	Protein_1706	transposase	-
FORC59_RS09100	1826720..1827094	-	375	WP_000695818.1	DUF1433 domain-containing protein	-
FORC59_RS09105	1827116..1827463	-	348	WP_001566695.1	DUF1433 domain-containing protein	-
FORC59_RS09110	1827673..1828116	-	444	WP_000742594.1	DUF1433 domain-containing protein	-
FORC59_RS09115	1828764..1829882	-	1119	WP_000072558.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1800236..1847770	47534

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T74357 WP_001801861.1 NZ_CP020354:1826053-1826148 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T74357 NZ_CP020354:1826053-1826148 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT74357 NZ_CP020354:c1826233-1826176 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin