74347

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 4816401..4817752 Replicon chromosome
Accession NZ_CP020350
Organism Pectobacterium brasiliense strain SX309

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag B5S52_RS21625 Protein ID WP_039510294.1
Coordinates 4816712..4817752 (+) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag B5S52_RS21620 Protein ID WP_039463512.1
Coordinates 4816401..4816715 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B5S52_RS21595 4812222..4813256 + 1035 WP_039510303.1 putative FMN-dependent luciferase-like monooxygenase -
B5S52_RS21600 4813253..4814386 + 1134 WP_039510302.1 alkylhydroperoxidase domain protein -
B5S52_RS21605 4814443..4814955 - 513 WP_164671834.1 phenolic acid decarboxylase -
B5S52_RS21610 4815055..4815927 + 873 WP_039510299.1 LysR family transcriptional regulator -
B5S52_RS21615 4816090..4816416 + 327 WP_039510297.1 helix-turn-helix domain-containing protein -
B5S52_RS21620 4816401..4816715 + 315 WP_039463512.1 HipA N-terminal domain-containing protein Antitoxin
B5S52_RS21625 4816712..4817752 + 1041 WP_039510294.1 HipA domain-containing protein Toxin
B5S52_RS21630 4817812..4818435 - 624 WP_039510292.1 LysE family translocator -
B5S52_RS21635 4818703..4819458 + 756 WP_039510290.1 thiol:disulfide interchange protein DsbG -
B5S52_RS21640 4819492..4820397 - 906 WP_039501750.1 siderophore-interacting protein -
B5S52_RS21645 4820652..4820903 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
B5S52_RS21650 4820900..4821187 + 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39602.63 Da        Isoelectric Point: 6.7794

>T74347 WP_039510294.1 NZ_CP020350:4816712-4817752 [Pectobacterium brasiliense]
MTRCRILLTPLTHEEEIATGYSRKGLKHLAGKMHASPTLRFTRQQFMHDLPQAQKGMSISGYQPKIQLVLEEQTFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKTHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLMHSRSGQLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAKCVESTYRDSFMP
ADAIETTLRCYRHRLNLMSILDAERI

Download         Length: 1041 bp

>T74347 NZ_CP020350:4816712-4817752 [Pectobacterium brasiliense]
ATGACAAGATGTCGAATTTTGCTGACACCGCTGACACACGAAGAAGAAATTGCCACAGGCTATAGCCGTAAAGGGTTGAA
GCATCTGGCGGGGAAAATGCACGCTTCCCCAACCTTACGTTTCACCCGCCAGCAATTTATGCACGACCTGCCACAAGCAC
AGAAAGGCATGAGTATCTCTGGCTATCAGCCCAAGATTCAGTTGGTATTAGAAGAACAGACGTTTACCGTCGTTGATCAT
CAAGGGCTATACATCCTCAAACCCTCTCCGATTGAATTTCCCCATTTGGCAGAAAATGAACATGCCACGATGACGCTAAT
GGCACGTCTGGGATTTGCCGTTCCACCACACGGGTTACTCCGTTTTAAACCGGAACAGGCGGATGACGAACCTGAGTTCG
CTTTCGTTATTAAGCGCTTCGACCGCGACGAAAAAACGGGTCACCCTATTCATCAGGAACAGTTGGACGGTGCGATGGGG
ATCGGTGAAAAATTCGGTAAAACACATACAGATGGCAGACAATACGTCAGTTATGAGCGGTTGGCTTTATTCCTTAGCAA
ACACGTTAATGACAATATCGTCTTCAAAATAGATCTGTTTCGCCGCATCGCTTACGCCTACATGTTGGGTAACAACGACA
TGCACCTGCGTAATTTTGGGCTGATGCATTCGCGCTCAGGCCAATTAATGCTGGCCCCTATTTATGACTTTGTTTCCGTC
GCCCCCTATCCCACCTATTTTTCTTCCTGTTTCATGGCATTGCCGCTGCTGATTCAAGAAGAGGGGGATGAGGCACTCGC
GCCAGGATTTGAAACTGCATACGGAGAATATCTTGGTATGGATTTCATTCTGTTCGGACAGCGTATTGGGCTGAGTGAAA
ACCTGACCAAAAAGCTATTGGCAGACTTCCTCAAAGAAGCTAAATGCGTTGAATCAACCTATCGAGATTCCTTTATGCCT
GCGGATGCTATTGAGACAACGCTGCGGTGCTATCGACACCGCCTGAATCTTATGAGCATTCTCGATGCAGAACGGATTTA
G

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11886.72 Da        Isoelectric Point: 9.7865

>AT74347 WP_039463512.1 NZ_CP020350:4816401-4816715 [Pectobacterium brasiliense]
MRRQVKVYLYGVHIGQLSQDDKGYLFEYKKSYIGPPLSLSLPIQTGTFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS

Download         Length: 315 bp

>AT74347 NZ_CP020350:4816401-4816715 [Pectobacterium brasiliense]
ATGCGCCGTCAAGTAAAGGTCTATCTTTACGGTGTCCACATCGGCCAGCTAAGTCAGGACGATAAAGGCTATTTGTTTGA
ATATAAAAAGTCCTACATCGGCCCGCCATTATCACTGAGCCTACCGATACAGACCGGAACATTTCGCAGCAAGACATTAC
CGCCTTATTTTGCCTCGTTAGCTCCCGAAGGCTGGCTCCGGCGGCAGTACAGCCAGCTTCAGCATCTGGATGAGAAGGAT
TTATTTGGCATCCTCATTCAAAACGGTAAGAACCTGATCGGCGCAGTACAGCTGATCGCGGAGGATAAGTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References