Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2458547..2458731 Replicon chromosome
Accession NZ_CP020020
Organism Staphylococcus aureus strain ATCC 6538

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag B4602_RS12830 Protein ID WP_000482647.1
Coordinates 2458624..2458731 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2458547..2458607 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4602_RS12805 2454001..2454168 - 168 WP_001790576.1 hypothetical protein -
B4602_RS12815 2454399..2456132 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
B4602_RS12820 2456157..2457920 - 1764 WP_001064814.1 ABC transporter ATP-binding protein/permease -
- 2458547..2458607 + 61 - - Antitoxin
B4602_RS12830 2458624..2458731 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
B4602_RS12835 2458865..2459251 - 387 WP_000779360.1 flippase GtxA -
B4602_RS12840 2459509..2460651 + 1143 WP_042727740.1 glycerate kinase -
B4602_RS12845 2460711..2461370 + 660 WP_000831298.1 membrane protein -
B4602_RS12850 2461552..2462763 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
B4602_RS12855 2462886..2463359 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T73785 WP_000482647.1 NZ_CP020020:c2458731-2458624 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T73785 NZ_CP020020:c2458731-2458624 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT73785 NZ_CP020020:2458547-2458607 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACTAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References