Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2197183..2197446 Replicon chromosome
Accession NZ_CP020019
Organism Staphylococcus aureus strain 08S00974

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag B4603_RS11275 Protein ID WP_001802298.1
Coordinates 2197342..2197446 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2197183..2197347 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B4603_RS11255 2193368..2194033 - 666 WP_001024099.1 SDR family oxidoreductase -
B4603_RS11260 2194185..2194505 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
B4603_RS11265 2194507..2195487 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
B4603_RS11270 2195753..2196844 + 1092 WP_000495673.1 hypothetical protein -
- 2197183..2197347 + 165 - - Antitoxin
B4603_RS11275 2197342..2197446 - 105 WP_001802298.1 hypothetical protein Toxin
B4603_RS11285 2198126..2198284 + 159 WP_001792784.1 hypothetical protein -
B4603_RS11290 2198720..2198812 + 93 WP_000220902.1 hypothetical protein -
B4603_RS11295 2198942..2199799 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
B4603_RS11300 2199867..2200649 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
B4603_RS11305 2200939..2201547 - 609 WP_000101714.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T73772 WP_001802298.1 NZ_CP020019:c2197446-2197342 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T73772 NZ_CP020019:c2197446-2197342 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT73772 NZ_CP020019:2197183-2197347 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References