Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3572637..3573236 Replicon chromosome
Accession NZ_CP019967
Organism Rhodopseudomonas palustris strain YSC3

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag RPYSC3_RS16455 Protein ID WP_107357551.1
Coordinates 3572637..3572921 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag RPYSC3_RS16460 Protein ID WP_107356106.1
Coordinates 3572934..3573236 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RPYSC3_RS16430 3567701..3567988 + 288 WP_107356101.1 hypothetical protein -
RPYSC3_RS16435 3568052..3568861 - 810 WP_107356102.1 DUF1295 domain-containing protein -
RPYSC3_RS16440 3568968..3569516 - 549 WP_107356103.1 hypothetical protein -
RPYSC3_RS16445 3569604..3571337 - 1734 WP_107356104.1 bifunctional protein-serine/threonine kinase/phosphatase -
RPYSC3_RS16450 3571406..3572245 - 840 WP_107356105.1 formate/nitrite transporter family protein -
RPYSC3_RS16455 3572637..3572921 + 285 WP_107357551.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RPYSC3_RS16460 3572934..3573236 + 303 WP_107356106.1 HigA family addiction module antidote protein Antitoxin
RPYSC3_RS16465 3573420..3574277 - 858 WP_107356107.1 SDR family oxidoreductase -
RPYSC3_RS16470 3574476..3576008 - 1533 WP_107345049.1 acyl-CoA carboxylase subunit beta -
RPYSC3_RS16475 3576286..3576702 + 417 WP_107356108.1 DUF4260 domain-containing protein -
RPYSC3_RS16480 3576706..3576981 - 276 WP_107356109.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-68)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10496.14 Da        Isoelectric Point: 10.3461

>T73631 WP_107357551.1 NZ_CP019967:3572637-3572921 [Rhodopseudomonas palustris]
MIQSFRGKFARAILQDRKAPKGLPADLLGTARRKLVQLNAAAALADLAIPPGNPLEALRGDLQGLHSIRINDQWRIVFRW
KDTGPEDVEIVDYH

Download         Length: 285 bp

>T73631 NZ_CP019967:3572637-3572921 [Rhodopseudomonas palustris]
ATGATCCAGAGCTTTCGAGGCAAGTTTGCTCGGGCGATTTTGCAGGACCGGAAAGCCCCCAAGGGCCTTCCGGCCGACCT
CCTGGGCACTGCCCGGCGCAAATTGGTTCAGCTCAACGCCGCCGCTGCTCTGGCCGACCTTGCGATCCCTCCCGGCAATC
CCCTGGAAGCCCTACGCGGAGATTTGCAGGGTCTCCATTCAATCCGGATCAACGATCAGTGGCGGATCGTGTTTCGCTGG
AAAGACACTGGTCCGGAAGACGTCGAGATCGTCGACTATCACTAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11309.06 Da        Isoelectric Point: 8.9890

>AT73631 WP_107356106.1 NZ_CP019967:3572934-3573236 [Rhodopseudomonas palustris]
MTKKLPPVHPGEILREEFLLPMNLSPYAVAAACGVPRTRIERLARQETPVTADTALRLARYFGTTPNFWMNLQAQYDLEV
AEDNSADELRRIKPIKSRAA

Download         Length: 303 bp

>AT73631 NZ_CP019967:3572934-3573236 [Rhodopseudomonas palustris]
ATGACGAAGAAACTACCCCCTGTTCACCCCGGCGAAATTCTCCGCGAAGAGTTTCTGCTGCCGATGAACCTGTCGCCCTA
CGCCGTCGCCGCAGCCTGCGGCGTACCGCGCACGCGCATCGAACGGCTGGCACGGCAGGAAACCCCAGTAACGGCGGACA
CCGCGCTGCGGCTGGCGAGATATTTCGGCACGACGCCGAATTTCTGGATGAACCTTCAGGCGCAGTACGATCTTGAAGTC
GCGGAAGACAACAGCGCCGACGAACTAAGGCGGATCAAGCCAATCAAGTCGAGAGCGGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References