Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2571038..2571222 Replicon chromosome
Accession NZ_CP019945
Organism Staphylococcus aureus strain BA01611

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag AOZ05_RS13630 Protein ID WP_000482647.1
Coordinates 2571115..2571222 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2571038..2571098 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOZ05_RS13600 2566568..2566735 - 168 WP_001790576.1 hypothetical protein -
AOZ05_RS13610 2566966..2568699 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
AOZ05_RS13615 2568724..2570487 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
- 2571038..2571098 + 61 - - Antitoxin
AOZ05_RS13630 2571115..2571222 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
AOZ05_RS13635 2571356..2571742 - 387 WP_000779360.1 flippase GtxA -
AOZ05_RS13640 2572000..2573142 + 1143 WP_001176863.1 glycerate kinase -
AOZ05_RS13645 2573202..2573861 + 660 WP_000831298.1 membrane protein -
AOZ05_RS13650 2574043..2575254 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
AOZ05_RS13655 2575377..2575850 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-134)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T73553 WP_000482647.1 NZ_CP019945:c2571222-2571115 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T73553 NZ_CP019945:c2571222-2571115 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT73553 NZ_CP019945:2571038-2571098 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References