Detailed information of TA system TA073543

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1946830..1947010
• Replicon: chromosome
• Accession: NZ_CP019945
• Organism: Staphylococcus aureus strain BA01611

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: AOZ05_RS15315
• Protein ID: WP_001801861.1
• Coordinates: 1946830..1946925 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1946953..1947010 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AOZ05_RS09960	1942206..1942949	+	744	WP_175393121.1	exotoxin	-
AOZ05_RS09965	1942976..1943728	+	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
AOZ05_RS09970	1943789..1944961	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
AOZ05_RS09975	1945192..1945748	-	557	Protein_1879	ImmA/IrrE family metallo-endopeptidase	-
AOZ05_RS09980	1945932..1946378	-	447	WP_000747805.1	DUF1433 domain-containing protein	-
AOZ05_RS15315	1946830..1946925	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1946953..1947010	-	58	-	-	Antitoxin
AOZ05_RS09990	1947576..1949271	-	1696	Protein_1882	hypothetical protein	-
AOZ05_RS10000	1949531..1950703	+	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
AOZ05_RS10005	1950755..1951435	-	681	Protein_1884	DNA adenine methylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	1938995..1970958	31963
	-	inside	IScluster/Tn	-	-	1943789..1950703	6914

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T73543 WP_001801861.1 NZ_CP019945:1946830-1946925 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T73543 NZ_CP019945:1946830-1946925 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT73543 NZ_CP019945:c1947010-1946953 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin