Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 72813..73315 Replicon chromosome
Accession NZ_CP019889
Organism Enterobacter hormaechei strain FRM

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag B1023_RS00355 Protein ID WP_032103793.1
Coordinates 73061..73315 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag B1023_RS00350 Protein ID WP_032103791.1
Coordinates 72813..73064 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B1023_RS00330 67935..68120 + 186 WP_001196016.1 hypothetical protein -
B1023_RS00335 68188..70284 + 2097 WP_045333527.1 peptidase domain-containing ABC transporter -
B1023_RS00340 70281..71030 + 750 WP_045348449.1 hypothetical protein -
B1023_RS00345 71037..72287 + 1251 WP_017693988.1 HlyD family efflux transporter periplasmic adaptor subunit -
B1023_RS00350 72813..73064 + 252 WP_032103791.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
B1023_RS00355 73061..73315 + 255 WP_032103793.1 Txe/YoeB family addiction module toxin Toxin
B1023_RS00360 73391..73708 + 318 WP_032103795.1 DUF1493 family protein -
B1023_RS00365 73733..74053 - 321 WP_032103796.1 type VI secretion system tube protein Hcp -
B1023_RS00370 74054..75142 - 1089 WP_023295682.1 AAA family ATPase -
B1023_RS00375 75289..76248 - 960 WP_017383648.1 DUF523 and DUF1722 domain-containing protein -
B1023_RS00380 76351..76761 - 411 WP_017383647.1 hydroxyisourate hydrolase -
B1023_RS00385 76861..77586 - 726 WP_032103799.1 MerR family transcriptional regulator -
B1023_RS00390 77704..78228 + 525 WP_032652079.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10089.65 Da        Isoelectric Point: 7.8740

>T73415 WP_032103793.1 NZ_CP019889:73061-73315 [Enterobacter hormaechei]
VKITWSEEAWEDYLYWQETDKRMVKKINELIKISCRTPFEGIGKPEPLKHNLAGFWSRRITSEHRMVYAITEEAILIAAC
RYHY

Download         Length: 255 bp

>T73415 NZ_CP019889:73061-73315 [Enterobacter hormaechei]
GTGAAGATCACATGGTCTGAAGAGGCATGGGAAGACTACCTCTATTGGCAGGAGACCGATAAGCGCATGGTGAAGAAAAT
CAATGAGCTTATCAAAATCTCCTGTCGCACTCCGTTTGAGGGGATCGGCAAGCCAGAGCCATTAAAACATAACCTGGCTG
GCTTCTGGTCTCGCCGAATCACCTCTGAGCATCGCATGGTCTATGCCATCACAGAAGAAGCGATCCTCATAGCTGCGTGC
CGATATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9313.55 Da        Isoelectric Point: 4.7854

>AT73415 WP_032103791.1 NZ_CP019889:72813-73064 [Enterobacter hormaechei]
MRVISYSEARQNLSATMVQTTEDRAPVLITRQNGESCVLMSLEEYNSLEETAYLMRSPANAKRLMNSIESLKSGGGKERD
IIE

Download         Length: 252 bp

>AT73415 NZ_CP019889:72813-73064 [Enterobacter hormaechei]
ATGCGTGTTATTAGTTACAGTGAAGCCCGACAAAACCTGTCGGCAACAATGGTCCAGACGACGGAAGATCGCGCGCCGGT
GCTTATTACGCGCCAGAACGGTGAATCTTGTGTTCTGATGTCGCTGGAAGAGTACAACTCGCTTGAAGAAACCGCATACC
TGATGCGCTCCCCGGCAAACGCAAAACGTCTGATGAACTCTATCGAGAGCTTGAAATCTGGTGGCGGGAAGGAAAGGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References