Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 4638759..4639417 Replicon chromosome
Accession NZ_CP019799
Organism Cellvibrio sp. PSBB023

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag B0D95_RS20020 Protein ID WP_078045522.1
Coordinates 4639067..4639417 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag B0D95_RS20015 Protein ID WP_078045847.1
Coordinates 4638759..4639061 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B0D95_RS20000 4634871..4636367 + 1497 WP_078045519.1 tryptophan 7-halogenase -
B0D95_RS20005 4636389..4638335 + 1947 WP_078045520.1 amylosucrase -
B0D95_RS20010 4638345..4638608 - 264 WP_078045521.1 hypothetical protein -
B0D95_RS20015 4638759..4639061 - 303 WP_078045847.1 helix-turn-helix domain-containing protein Antitoxin
B0D95_RS20020 4639067..4639417 - 351 WP_078045522.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B0D95_RS20025 4639571..4640629 - 1059 WP_078045523.1 arabinan endo-1,5-alpha-L-arabinosidase -
B0D95_RS20030 4640738..4641835 + 1098 WP_078045524.1 glycoside hydrolase family 43 protein -
B0D95_RS20035 4641901..4642980 + 1080 WP_078045525.1 galactose mutarotase -
B0D95_RS20040 4643079..4643270 - 192 WP_078045526.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4626532..4639417 12885


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-81)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13307.29 Da        Isoelectric Point: 6.4685

>T73318 WP_078045522.1 NZ_CP019799:c4639417-4639067 [Cellvibrio sp. PSBB023]
MWEIETTDTFDKWFDELEDSDRASVIASLLLLKEKGPQLARPYADTVKGSVHGNMKELRVQSNGEPIRAFFAFDPLRRGI
LLCAGCKTGDEKRFYKIMIPIADREFTAHLKTLETR

Download         Length: 351 bp

>T73318 NZ_CP019799:c4639417-4639067 [Cellvibrio sp. PSBB023]
ATGTGGGAAATAGAGACGACCGATACCTTTGATAAGTGGTTTGATGAATTGGAGGATAGCGACAGGGCCAGCGTAATCGC
CTCACTGTTGCTACTGAAGGAAAAAGGGCCGCAACTCGCAAGGCCCTACGCAGACACAGTAAAGGGCTCAGTTCACGGCA
ACATGAAGGAACTACGAGTGCAGAGTAACGGAGAGCCTATTCGGGCCTTCTTTGCATTCGACCCGTTGCGCCGAGGAATT
CTACTCTGTGCGGGTTGTAAAACTGGCGATGAAAAACGGTTTTATAAAATCATGATCCCAATAGCAGACAGAGAATTTAC
CGCTCATTTAAAGACATTGGAAACGAGGTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11076.83 Da        Isoelectric Point: 5.7378

>AT73318 WP_078045847.1 NZ_CP019799:c4639061-4638759 [Cellvibrio sp. PSBB023]
VARTLEQILANEKPEVVAQAREQADAMLLNIHLAELRELVDKTQMEIAAALGVKQPTIAEMEKVGRDIKLSSLKRYVEAT
GGKLRLDIELPNGTHWGFSV

Download         Length: 303 bp

>AT73318 NZ_CP019799:c4639061-4638759 [Cellvibrio sp. PSBB023]
GTGGCCAGAACATTAGAACAGATACTTGCAAACGAAAAACCAGAGGTCGTGGCCCAAGCTCGTGAGCAAGCAGATGCAAT
GCTGCTTAATATCCATTTAGCGGAGTTACGTGAACTCGTAGACAAAACGCAAATGGAAATTGCTGCGGCGCTTGGCGTTA
AGCAGCCCACGATTGCAGAAATGGAGAAGGTCGGTAGAGATATAAAACTTTCTTCCTTGAAGCGCTATGTAGAAGCAACG
GGTGGAAAGTTACGCCTGGATATTGAATTACCAAATGGGACTCATTGGGGATTCAGTGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References