Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 611731..612384 Replicon chromosome
Accession NZ_CP019791
Organism Anaerohalosphaera lusitana strain ST-NAGAB-D1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag STSP2_RS02650 Protein ID WP_146659613.1
Coordinates 612034..612384 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag STSP2_RS02645 Protein ID WP_146659611.1
Coordinates 611731..612030 (-) Length 100 a.a.

Genomic Context

STSP2_RS02640STSP2_RS02635STSP2_RS02645STSP2_RS02650STSP2_RS02655STSP2_RS02660STSP2_RS02665STSP2_RS02670STSP2_RS02675
Location: 609261..611714 (2454 bp)
Type: Others
Protein ID: WP_169852926.1
Location: 608453..608995 (543 bp)
Type: Others
Protein ID: WP_146659607.1
Location: 611731..612030 (300 bp)
Type: Antitoxin
Protein ID: WP_146659611.1
Location: 612034..612384 (351 bp)
Type: Toxin
Protein ID: WP_146659613.1
Location: 612459..613007 (549 bp)
Type: Others
Protein ID: WP_146659615.1
Location: 613000..613455 (456 bp)
Type: Others
Protein ID: WP_146659617.1
Location: 613458..614432 (975 bp)
Type: Others
Protein ID: WP_146659619.1
Location: 614895..615281 (387 bp)
Type: Others
Protein ID: WP_146659621.1
Location: 615549..616670 (1122 bp)
Type: Others
Protein ID: WP_146659623.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
STSP2_RS02635608453..608995-543WP_146659607.1GNAT family N-acetyltransferase-
STSP2_RS02640609261..611714+2454WP_169852926.1PASTA domain-containing protein-
STSP2_RS02645611731..612030-300WP_146659611.1helix-turn-helix transcriptional regulatorAntitoxin
STSP2_RS02650612034..612384-351WP_146659613.1type II toxin-antitoxin system RelE/ParE family toxinToxin
STSP2_RS02655612459..613007-549WP_146659615.1GNAT family N-acetyltransferase-
STSP2_RS02660613000..613455-456WP_146659617.1hypothetical protein-
STSP2_RS02665613458..614432-975WP_146659619.1ADP-glyceromanno-heptose 6-epimerase-
STSP2_RS02670614895..615281-387WP_146659621.1response regulator-
STSP2_RS02675615549..616670-1122WP_146659623.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

HigA2-like, helix-turn-helix domain

(17-86)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13782.76 Da        Isoelectric Point: 10.1420

>T73312 WP_146659613.1 NZ_CP019791:c612384-612034 [Anaerohalosphaera lusitana]
MWEVEFTDEFEKWWQTLDVKQQEDVLVSVELLRNLGPHLARPYADTVKGSKHKNMKELRTQSKGRPLRTFYAFDPRRYAV
LLLGGDKKGNSRFYQQLINKADQIYDRHLNDIKKKG

Download         Length: 351 bp

>T73312 NZ_CP019791:c612384-612034 [Anaerohalosphaera lusitana]
ATGTGGGAAGTGGAGTTCACAGACGAATTTGAGAAATGGTGGCAAACTCTGGACGTCAAGCAACAGGAAGATGTTCTGGT
CAGTGTCGAGTTGCTCAGGAATCTTGGTCCGCATCTTGCCCGGCCTTATGCCGACACAGTCAAGGGTTCCAAACACAAGA
ATATGAAGGAACTAAGAACTCAAAGCAAGGGCAGACCTCTGCGTACTTTTTATGCTTTCGATCCGAGACGATACGCAGTA
CTGCTGCTGGGCGGCGACAAAAAGGGAAACAGTAGATTTTACCAGCAACTTATCAACAAGGCTGACCAAATTTATGATCG
GCACTTGAATGATATAAAGAAAAAGGGGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11266.19 Da        Isoelectric Point: 10.4169

>AT73312 WP_146659611.1 NZ_CP019791:c612030-611731 [Anaerohalosphaera lusitana]
VARKFSELEKRMDPESVKRAKARAREEMAQMLLAEIRKETGITQENLAKSMGIKQPSLSKLESQRDMQISTLRRLIEALG
GKLELIAHMPEGDIKISQF

Download         Length: 300 bp

>AT73312 NZ_CP019791:c612030-611731 [Anaerohalosphaera lusitana]
GTGGCACGTAAATTTTCAGAACTCGAAAAACGTATGGATCCTGAAAGCGTCAAACGAGCTAAGGCCCGAGCCAGGGAAGA
AATGGCTCAGATGCTCTTGGCCGAGATCCGAAAAGAAACAGGCATCACGCAGGAAAATCTCGCCAAAAGCATGGGAATCA
AACAGCCAAGCCTTTCCAAGTTGGAGTCACAGCGTGACATGCAGATAAGCACGCTGCGAAGGCTAATCGAGGCTCTGGGC
GGCAAACTCGAACTGATCGCCCACATGCCCGAGGGCGACATAAAGATAAGTCAATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References