Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2867788..2868335 Replicon chromosome
Accession NZ_CP019725
Organism Xanthomonas perforans 91-118

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag XPE_RS12895 Protein ID WP_074053292.1
Coordinates 2867788..2868027 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag XPE_RS12900 Protein ID WP_008571772.1
Coordinates 2868045..2868335 (+) Length 97 a.a.

Genomic Context

XPE_RS12890XPE_RS12895XPE_RS12900XPE_RS12910XPE_RS22470XPE_RS12920XPE_RS12930
Location: 2865315..2867690 (2376 bp)
Type: Others
Protein ID: WP_046932680.1
Location: 2867788..2868027 (240 bp)
Type: Toxin
Protein ID: WP_074053292.1
Location: 2868045..2868335 (291 bp)
Type: Antitoxin
Protein ID: WP_008571772.1
Location: 2868684..2870078 (1395 bp)
Type: Others
Protein ID: WP_008571771.1
Location: 2870181..2870360 (180 bp)
Type: Others
Protein ID: WP_003482327.1
Location: 2870428..2872353 (1926 bp)
Type: Others
Protein ID: WP_033478553.1
Location: 2872689..2873021 (333 bp)
Type: Others
Protein ID: WP_003482333.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XPE_RS128902865315..2867690+2376WP_046932680.1AAA family ATPase-
XPE_RS128952867788..2868027+240WP_074053292.1type II toxin-antitoxin system RelE/ParE family toxinToxin
XPE_RS129002868045..2868335+291WP_008571772.1HigA family addiction module antidote proteinAntitoxin
XPE_RS129102868684..2870078+1395WP_008571771.1nucleoside hydrolase-
XPE_RS224702870181..2870360-180WP_003482327.1hypothetical protein-
XPE_RS129202870428..2872353-1926WP_033478553.1M61 family metallopeptidase-
XPE_RS129302872689..2873021-333WP_003482333.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-79)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-66)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9270.65 Da        Isoelectric Point: 9.9836

>T73220 WP_074053292.1 NZ_CP019725:2867788-2868027 [Xanthomonas perforans 91-118]
MGERSRRLPADIQLVARRTLRMLNAAAHLDNLRIPPANRLEASKGERPGQYSIRINDQWRICFRWMEGDVVQVEIVDYH

Download         Length: 240 bp

>T73220 NZ_CP019725:2867788-2868027 [Xanthomonas perforans 91-118]
CTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCAATTGGTCGCGCGCCGCACGTTGCGCATGCTCAATGCCGCCGC
GCATCTCGACAATCTGCGGATTCCGCCCGCCAACCGGCTGGAAGCGTCGAAGGGCGAGCGGCCCGGCCAGTACAGCATCC
GGATCAACGATCAATGGCGCATCTGCTTCCGATGGATGGAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10337.97 Da        Isoelectric Point: 6.4665

>AT73220 WP_008571772.1 NZ_CP019725:2868045-2868335 [Xanthomonas perforans 91-118]
MTVLPNIHPGEILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERVWLGLQADDELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT73220 NZ_CP019725:2868045-2868335 [Xanthomonas perforans 91-118]
ATGACGGTCCTACCCAATATCCACCCTGGCGAAATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGTCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGAACCTCCGAGCGCGTCTGGCTTGGCCTGCAGGCCGACGACGAACTGGAGCAGGCG
CATCGCGCGCTGGGCGACTTGCCGGCGCGGATCAAGCGGCTGGCGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References