73162

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 621984..623314 Replicon chromosome
Accession NZ_CP019686
Organism Proteus sp. CD3

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag BTA34_RS02725 Protein ID WP_151434397.1
Coordinates 621984..623006 (-) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag BTA34_RS02730 Protein ID WP_151434398.1
Coordinates 623003..623314 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTA34_RS02715 (BTA34_02720) 617045..619477 + 2433 WP_151434395.1 ATP-dependent helicase HrpB -
BTA34_RS02720 (BTA34_02725) 619617..621923 + 2307 WP_151434396.1 bifunctional glycosyl transferase/transpeptidase -
BTA34_RS02725 (BTA34_02730) 621984..623006 - 1023 WP_151434397.1 HipA domain-containing protein Toxin
BTA34_RS02730 (BTA34_02735) 623003..623314 - 312 WP_151434398.1 HipA N-terminal domain-containing protein Antitoxin
BTA34_RS02735 (BTA34_02740) 623299..623649 - 351 WP_151434399.1 XRE family transcriptional regulator -
BTA34_RS02740 (BTA34_02745) 623960..625246 - 1287 WP_151434400.1 glutamate-1-semialdehyde 2,1-aminomutase -
BTA34_RS02745 (BTA34_02750) 625522..625866 + 345 WP_006534944.1 iron-sulfur cluster insertion protein ErpA -
BTA34_RS02750 (BTA34_02755) 626585..627103 + 519 WP_151434401.1 Hcp family type VI secretion system effector -
BTA34_RS02755 (BTA34_02760) 627393..628220 - 828 WP_151434402.1 vitamin B12 ABC transporter substrate-binding protein BtuF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-295)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38789.65 Da        Isoelectric Point: 6.0576

>T73162 WP_151434397.1 NZ_CP019686:c623006-621984 [Proteus sp. CD3]
MNVNNCLINLKELKRSELDSGYSLLGIKSLFNNIDIILNLPFTRSQFIQELPEQQKGMSISGYQPKLSLCVKDNILKVVN
NNGTYILKPSPEEYPYLAENEHATMMVMQRLKFDIPPFGLFRFKQEDGKPEEFAFVIKRYDRIGSDAVRLHQEQLDGAMG
INDKYGLSKGKKTVSYESAAKYLITNIDNSLKNKRDIFLRIVYAYVLGNNDYHLRNMGIILPDNASPSLAPVYDFVSVVP
YPSAFTEYLALPLLALEENDTDTAPGLNSKYGEYIGFDFILLAENIDINLKLAQKWLGDIINSHQLIIDTYNESHMPKEQ
RELVLAYVARRINLLKITTL

Download         Length: 1023 bp

>T73162 NZ_CP019686:c623006-621984 [Proteus sp. CD3]
ATGAATGTAAACAATTGTTTAATAAATCTAAAAGAACTAAAAAGATCAGAATTAGATTCAGGCTATTCTCTACTCGGGAT
AAAATCTCTTTTTAACAATATAGACATAATCCTGAATTTACCCTTTACACGTAGTCAATTCATTCAAGAATTACCTGAAC
AACAAAAAGGGATGAGTATTTCAGGTTATCAGCCAAAACTCTCACTATGTGTAAAAGATAACATTCTAAAAGTCGTTAAT
AATAACGGTACTTATATCCTCAAACCTTCACCTGAAGAATATCCTTATCTCGCTGAAAATGAACATGCGACCATGATGGT
AATGCAACGGCTAAAATTTGATATTCCACCATTTGGTCTTTTTCGTTTTAAACAAGAAGATGGAAAGCCAGAAGAATTTG
CTTTTGTTATTAAGCGATATGATCGTATTGGTTCTGATGCAGTTCGGTTACATCAAGAACAATTAGATGGTGCGATGGGG
ATAAATGATAAATATGGGCTTTCTAAGGGGAAAAAGACTGTTAGCTATGAATCTGCTGCAAAATATTTAATTACTAATAT
AGATAATAGTCTTAAAAATAAACGAGATATTTTTCTGCGTATCGTTTATGCCTATGTTTTAGGAAACAATGATTATCACT
TAAGAAATATGGGTATCATTTTACCTGATAACGCGTCTCCATCACTAGCGCCAGTTTATGATTTTGTCAGTGTAGTCCCT
TATCCATCGGCATTTACAGAATATCTTGCACTCCCATTACTTGCATTAGAAGAAAACGATACAGACACAGCCCCAGGATT
AAATTCAAAATATGGTGAGTATATTGGGTTTGATTTCATTCTACTGGCGGAAAATATTGATATTAACCTTAAGCTTGCTC
AAAAATGGCTAGGCGATATTATAAATAGTCACCAACTCATTATTGATACATATAATGAAAGTCATATGCCCAAAGAACAA
AGAGAATTAGTCTTAGCTTATGTAGCAAGAAGAATAAACTTACTCAAAATAACTACGCTATAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12163.97 Da        Isoelectric Point: 5.6505

>AT73162 WP_151434398.1 NZ_CP019686:c623314-623003 [Proteus sp. CD3]
MPRKIEVWLYDQPAGVLSEEENGFIFHYYDNYKGRAISLSMPVRKEHYWCEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMNNGNDLLGAVVLREITL

Download         Length: 312 bp

>AT73162 NZ_CP019686:c623314-623003 [Proteus sp. CD3]
ATGCCTCGAAAAATAGAAGTTTGGCTTTATGACCAACCTGCTGGTGTTTTAAGTGAAGAAGAAAATGGGTTTATTTTTCA
CTATTATGATAACTACAAGGGCAGAGCAATATCTTTAAGTATGCCGGTTAGAAAAGAGCATTATTGGTGTGAAGAATTAC
ATCCTTTTTTCAAAGGATTAGCACCAGAAGGATGGTTACGTAAACGTTACTCTGAAATTCAGAAAATTGATGATAAAGAT
TTGTTTGGTCTATTGATGAACAATGGTAATGACTTACTAGGGGCAGTTGTCCTTAGAGAGATAACCCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References