Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2481482..2481666 Replicon chromosome
Accession NZ_CP019595
Organism Staphylococcus aureus strain GD1677

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag BZK09_RS12755 Protein ID WP_000482647.1
Coordinates 2481559..2481666 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2481482..2481542 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZK09_RS12730 2476936..2477103 - 168 WP_001798790.1 hypothetical protein -
BZK09_RS12740 2477334..2479067 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
BZK09_RS12745 2479092..2480855 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2481482..2481542 + 61 - - Antitoxin
BZK09_RS12755 2481559..2481666 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
BZK09_RS12760 2481800..2482186 - 387 WP_000779355.1 flippase GtxA -
BZK09_RS12765 2482453..2483595 + 1143 WP_001176859.1 glycerate kinase -
BZK09_RS12770 2483655..2484314 + 660 WP_000831300.1 hypothetical protein -
BZK09_RS12775 2484502..2485713 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
BZK09_RS12780 2485836..2486309 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T72804 WP_000482647.1 NZ_CP019595:c2481666-2481559 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T72804 NZ_CP019595:c2481666-2481559 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT72804 NZ_CP019595:2481482-2481542 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References