Detailed information of TA system TA072798

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1070893..1071142
• Replicon: chromosome
• Accession: NZ_CP019595
• Organism: Staphylococcus aureus strain GD1677

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: BZK09_RS05450
• Protein ID: WP_000623369.1
• Coordinates: 1070893..1071000 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1070995..1071142 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BZK09_RS05425	1067567..1068136	-	570	WP_000287265.1	competence protein ComK	-
BZK09_RS05430	1068346..1068564	+	219	WP_000876826.1	IDEAL domain-containing protein	-
BZK09_RS05435	1068645..1069631	-	987	WP_000668814.1	lipoate--protein ligase	-
BZK09_RS05440	1069830..1070006	+	177	WP_000214898.1	YkvS family protein	-
BZK09_RS05445	1070021..1070623	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
BZK09_RS05450	1070893..1071000	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1070995..1071142	-	148	-	-	Antitoxin
BZK09_RS05455	1071635..1071919	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
BZK09_RS05460	1071963..1073927	+	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
BZK09_RS05465	1073930..1074250	+	321	WP_000668623.1	YxeA family protein	-
BZK09_RS05470	1074247..1074888	+	642	WP_000571192.1	ABC transporter ATP-binding protein	-
BZK09_RS05475	1074976..1075266	-	291	WP_001796515.1	hypothetical protein	-
BZK09_RS05480	1075356..1075544	+	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
BZK09_RS05485	1075633..1075989	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T72798 WP_000623369.1 NZ_CP019595:1070893-1071000 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T72798 NZ_CP019595:1070893-1071000 [Staphylococcus aureus]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT72798 NZ_CP019595:c1071142-1070995 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin