72761

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2475189..2475373 Replicon chromosome
Accession NZ_CP019592
Organism Staphylococcus aureus strain GD5

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag BZJ79_RS12780 Protein ID WP_000482647.1
Coordinates 2475266..2475373 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2475189..2475249 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZJ79_RS12755 2470643..2470810 - 168 WP_001798790.1 hypothetical protein -
BZJ79_RS12765 2471041..2472774 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
BZJ79_RS12770 2472799..2474562 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2475189..2475249 + 61 - - Antitoxin
BZJ79_RS12780 2475266..2475373 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
BZJ79_RS12785 2475507..2475893 - 387 WP_000779355.1 flippase GtxA -
BZJ79_RS12790 2476160..2477302 + 1143 WP_001176859.1 glycerate kinase -
BZJ79_RS12795 2477362..2478021 + 660 WP_000831300.1 hypothetical protein -
BZJ79_RS12800 2478209..2479420 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
BZJ79_RS12805 2479543..2480016 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T72761 WP_000482647.1 NZ_CP019592:c2475373-2475266 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T72761 NZ_CP019592:c2475373-2475266 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT72761 NZ_CP019592:2475189-2475249 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References